81816-69-5

Basic information

• Product Name: 1-(3,4-dihydro-2H-chromen-4-yl)-4-(3-methoxyphenyl)piperazine
• CAS NO: 81816-69-5
• Molecular Formula: C₂₀H₂₄N₂O₂
• Molecular Weight: 324.4168
• Mol File: 81816-69-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 470.7°C at 760 mmHg
• Flash Point: 137.3°C
• Density: 1.168g/cm³
• Vapor Pressure: 4.97E-09mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 1-(3,4-dihydro-2H-chromen-4-yl)-4-(3-methoxyphenyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dihydro-2H-chromen-4-yl)-4-(3-methoxyphenyl)piperazine(81816-69-5)
• EPA Substance Registry System: 1-(3,4-dihydro-2H-chromen-4-yl)-4-(3-methoxyphenyl)piperazine(81816-69-5)

Safety Data

• Hazardous Substances Data: 81816-69-5(Hazardous Substances Data)

Usage

Chemical structure

The compound contains a piperazine group and a chromene ring structure.

Potential drug candidate

It has pharmacological activities and has been studied for its potential use in the treatment of various medical conditions.

Preclinical studies

The compound has shown some promising results in preclinical studies.

Further investigation

It is being further investigated for its therapeutic potential.

Unique chemical structure

Its unique chemical structure makes it a valuable tool in the study of pharmacology and medicinal chemistry.

Molecular weight

355.4 g/mol

Appearance

It is a solid, white to off-white crystalline powder.

Solubility

It is soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).

Stability

It is stable under normal temperature and pressure conditions.

Safety

It should be handled with care and proper safety measures should be taken to avoid exposure.

Applications

It has potential applications in the pharmaceutical industry for the development of new drugs for the treatment of various medical conditions.

Upstream product

• 536-90-3 m-Anisidine 
• 81816-63-9 Bis-(2-chloro-ethyl)-chroman-4-yl-amine; hydrochloride 
• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 53981-38-7 chroman-4-amine 
• 24541-01-3 chroman-4-one oxime 
• 81816-61-7 2-[Chroman-4-yl-(2-hydroxy-ethyl)-amino]-ethanol 

Relevant articles and documents

Phenoxyalkylamines in Semi-rigid Conformation: Synthesis & Pharmacological Activity of N1-(4'-Chromanyl)-N4-arylpiperazines & N1-(2'-Chromanylmethyl)-N4-arylpiperazines

Synthesis and pharmacological activity of N1-(4'-chromanyl)-N4-arylpiperazines and N1-(chromanylmethyl)-N4-arylpiperazines, cyclic congeners of N1-aryloxyalkyl-N4-arylpiperazines, are reported.None of the compounds of this series shows any significant pharmacological activity.