81824-11-5

Basic information

• Product Name: (11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol
• Synonyms: Benz(e)acephenanthrylene-11,12-diol, 11,12-dihydro-, trans-
• CAS NO: 81824-11-5
• Molecular Formula: C₂₀H₁₄O₂
• Molecular Weight: 286.324
• Mol File: 81824-11-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 553.3°C at 760 mmHg
• Flash Point: 268.6°C
• Density: 1.46g/cm³
• Vapor Pressure: 4.47E-13mmHg at 25°C
• Refractive Index: 1.911
• CAS DataBase Reference: (11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol(81824-11-5)
• EPA Substance Registry System: (11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol(81824-11-5)

Safety Data

• Hazardous Substances Data: 81824-11-5(Hazardous Substances Data)

Usage

Description

(11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol is a chemical compound with a unique molecular structure, characterized by its benzo[e]acephenanthrylene core and two hydroxyl groups at the 11 and 12 positions. It exhibits mutagenic and potential carcinogenic properties, making it a significant compound for research purposes.

Uses

Used in Biological Research:
(11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol is used as a research compound for studying tumorigenicity. Its mutagenic and potential carcinogenic properties make it a valuable tool for understanding the mechanisms behind cancer development and progression.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol may be utilized as a lead compound for the development of novel anticancer drugs. Its mutagenic and carcinogenic properties could provide insights into the design of more effective cancer therapies and help in the identification of potential drug targets.
Used in Environmental Studies:
(11S,12S)-11,12-dihydrobenzo[e]acephenanthrylene-11,12-diol can also be employed in environmental studies to assess the presence of mutagenic and carcinogenic compounds in the environment. This information can be crucial for understanding the impact of environmental pollutants on human health and for developing strategies to mitigate their effects.

Upstream product

• 88746-67-2 9-bromo-11β,12α-bis(benzoyloxy)-9,10,11,12-tetrahydrobenzofluoranthene 
• 88746-66-1 trans-11,12-bis(benzoyloxy)-9,10,11,12-tetrahydrobenzofluoranthene 
• 88746-62-7 4-(2-fluoranthenyl)butyric acid 
• 88746-64-9 12-hydroxy-9,10,11,12-tetrahydrobenzofluoranthene 
• 88746-63-8 12-oxo-9,10,11,12-tetrahydrobenzofluoranthene 
• 88746-61-6 4-(2-fluoranthenyl)butyraldehyd 
• 88746-60-5 4-(2-fluoranthenyl)-1-butanol 
• 88746-58-1 2-(bromomethyl)fluoranthene 
• 88746-65-0 9,10-dihydrobenzofluoranthene 
• 88746-59-2 4-(2-fluoranthenyl)-1-butene 
• 33543-31-6 2-methylfluoranthene 
• 88746-68-3 trans-11,12-bis(benzoyloxy)-11,12-dihydrobenzofluoranthene 

Relevant articles and documents

Synthesis and Mutagenicity of Dihydrodiol Metabolites of Benzofluoranthene

The syntheses of the two major hepatic microsomal dihydrodiol metabolites of the environmental carcinogen, benzofluoranthene, are described. 1,2-Dihydro-1,2-dihydroxybenzofluoranthene was prepared from 11H-benzofluorene-11-carboxylic acid.The key