818377-08-1

Basic information

• Product Name: (S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanol
• Synonyms: (S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanol
• CAS NO: 818377-08-1
• Molecular Weight: 321.462
• Mol File: 818377-08-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanol(818377-08-1)
• EPA Substance Registry System: (S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanol(818377-08-1)

Safety Data

• Hazardous Substances Data: 818377-08-1(Hazardous Substances Data)

Upstream product

• 134-63-4 Lobeline hydrochloride 

Downstream Products

• 530-51-8 N-methyl-2,6-di-(cis-phenylethyl)piperidine 
• 946486-28-8 2-[(R)-1-Methyl-6-((E)-styryl)-piperidin-2-yl]-1-phenyl-ethanone 
• 758717-85-0 (2S,6R)-1-Methyl-2,6-bis-((E)-styryl)-piperidine 
• 818377-12-7 (2R,6R)-1-Methyl-2,6-bis-((E)-styryl)-piperidine 

Relevant articles and documents

Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters

A series of des-keto lobeline analogs has been synthesized and evaluated for their ability to inhibit the dopamine transporter (DAT) and serotonin transporter (SERT) function and for their affinity for the synaptic vesicle monoamine transporter (VMAT2), a

Lobeline: Structure-affinity investigation of nicotinic acetylcholinergic receptor binding

(-)Lobeline (1) and (-)nicotine (2) bind at neuronal nicotinic cholinergic (nACh) receptors with high affinity (K1 = 4 and 2 nM, respectively). Previous attempts to determine whether lobeline fits the currently accepted nicotinic pharmacophore