81864-47-3

Basic information

• Product Name: 6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL
• Synonyms: 6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL;5,6-ETHYLENEDIOXY-2-MERCAPTOBENZIMIDAZOLE;1,3,6,7-Tetrahydro-2H-[1,4]dioxino[2,3-f]-benzimidazole-2-thione;1,3,6,7-tetrahydro-[1,4]dioxino[2,3-f]benzimidazole-2-thione;BB_SC-4870;Maybridge1_002185;MLS000851100;Oprea1_185537
• CAS NO: 81864-47-3
• Molecular Formula: C9H8N2O2S
• Molecular Weight: 208.24
• Mol File: 81864-47-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 300 °C
• Boiling Point: 352.3°C at 760 mmHg
• Flash Point: 166.9°C
• Appearance: /
• Density: 1.55g/cm³
• Vapor Pressure: 3.88E-05mmHg at 25°C
• Refractive Index: 1.748
• PKA: 11.16±0.20(Predicted)
• CAS DataBase Reference: 6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL(81864-47-3)
• EPA Substance Registry System: 6,7-DIHYDRO-1H-[1,4]DIOXINO[2',3':4,5]BENZO[D]IMIDAZOLE-2-THIOL(81864-47-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 81864-47-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8N2O2S/c14-9-10-5-3-7-8(4-6(5)11-9)13-2-1-12-7/h3-4H,1-2H2,(H2,10,11,14)

Upstream product

• 63546-22-5 6-acetamido-7-nitro-2,3-dihydro-1,4-benzodioxine 
• 62140-78-7 7-nitro-2,3-dihydro-1,4-benzodioxin-6-amine 
• 22013-33-8 6-amino-3,4-benzodioxane 
• 63546-19-0 N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide 
• 81927-47-1 7-amino-2,3-dihydro-1,4-benzodioxin-6-ylamine 
• 140-89-6 potassium ethyl xanthogenate 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The present invention relates to benzimidazole derivatives and their pharmaceutical compositions and uses, specifically to benzimidazole derivatives of Formula (I), or their stereoisomer, pharmaceutically acceptable salt or solvates thereof, in which R1, R2, R3, R4, R5 and n have the definitions in the description; the present invention further relates to a pharmaceutical composition containing the compounds, methods for preparing the compounds, and use of the compounds for manufacturing of a medicament for prophylaxis and/or treatment of peptic ulcer, ulcer hemorrhage and diseases associated with gastric acid.