81864-62-2

Basic information

• Product Name: 10-nitro-2,6-dioxabicyclo[5.4.0]undeca-8,10,12-trien-9-amine
• Synonyms: 10-nitro-2,6-dioxabicyclo[5.4.0]undeca-8,10,12-trien-9-amine;8-Nitro-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-aMine;3,4-Dihydro-8-nitro-2H-benzo[b][1,4]dioxepin-7-amine
• CAS NO: 81864-62-2
• Molecular Formula: C9H10N2O4
• Molecular Weight: 210.188
• Mol File: 81864-62-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 390.6°Cat760mmHg
• Flash Point: 190°C
• Appearance: /
• Density: 1.399g/cm³
• Vapor Pressure: 2.62E-06mmHg at 25°C
• Refractive Index: 1.614
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 10-nitro-2,6-dioxabicyclo[5.4.0]undeca-8,10,12-trien-9-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 10-nitro-2,6-dioxabicyclo[5.4.0]undeca-8,10,12-trien-9-amine(81864-62-2)
• EPA Substance Registry System: 10-nitro-2,6-dioxabicyclo[5.4.0]undeca-8,10,12-trien-9-amine(81864-62-2)

Safety Data

• Hazardous Substances Data: 81864-62-2(Hazardous Substances Data)

Usage

General Description

The chemical 10-nitro-2,6-dioxabicyclo[5.4.0]undeca-8,10,12-trien-9-amine, also known as NDBU, is a nitro-substituted aromatic amine compound. It is a versatile building block used in organic synthesis and medicinal chemistry. NDBU has been investigated for its potential use in the development of pharmaceuticals and bioactive compounds, due to its unique chemical structure and reactivity. Its synthesis and functionalization have been the subject of research studies to explore its potential applications in various fields, including the pharmaceutical industry and material science.

InChI:InChI=1/C9H10N2O4/c10-6-4-8-9(5-7(6)11(12)13)15-3-1-2-14-8/h4-5H,1-3,10H2

Upstream product

• 135399-50-7 7,8-dinitro-3,4-dihydro-2H-benzo<1,4>dioxepin 
• 81864-61-1 7-acetamino-8-nitro-3,4-dihydro-2H-1,5-benzodioxepine 

Relevant articles and documents

Quinoxaline compound, preparation method and application of quinoxaline compound in medicine

The invention provides a quinoxaline compound, a preparation method and application of the quinoxaline compound in medicine, and particularly relates to a quinoxaline compound with PAR4 antagonistic activity, a preparation method of the quinoxaline compound, a pharmaceutical composition containing the quinoxaline compound and application of the quinoxaline compound. Specifically, the invention provides a compound shown as a general formula I and/or II or a tautomer or pharmaceutically acceptable salt thereof, a preparation method of the compound, and application of the compound or the tautomer or the pharmaceutically acceptable salt in medicines for preventing and/or treating thromboembolic diseases.

Imidazole derivatives

Tricyclic imidazole derivatives of the formula STR1 wherein R1 is 2-pyridyl optionally substituted by lower alkyl or lower alkoxy, n is the integer 0 or 1, R2 is hydrogen or lower alkyl, R3 and R4, independently, are hydrogen or lower alkyl, A is a group of the formula STR2 m is the integer 2 or 3, R5, R6, R7 and R8, independently, are hydrogen or lower alkyl, and R9 is hydrogen and R10 is hydrogen or lower alkyl or R9 and R10 taken together are oxo, provided that at least one of R3 and R4 is lower alkyl when A is a group of the formula and their pharmaceutically acceptable acid addition salts. The compounds of formula I inhibit gastric acid secretion and prevent the formation of gastric ulcers.