81872-42-6

Basic information

• Product Name: 2-(2-phenyl-2H-1,2,3-triazol-4-yl)tetrahydrofuran-3,4-diol
• CAS NO: 81872-42-6
• Molecular Formula: C₁₂H₁₃N₃O₃
• Molecular Weight: 247.2499
• Mol File: 81872-42-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 517.1°C at 760 mmHg
• Flash Point: 266.5°C
• Density: 1.53g/cm³
• Vapor Pressure: 1.61E-11mmHg at 25°C
• Refractive Index: 1.713
• CAS DataBase Reference: 2-(2-phenyl-2H-1,2,3-triazol-4-yl)tetrahydrofuran-3,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-phenyl-2H-1,2,3-triazol-4-yl)tetrahydrofuran-3,4-diol(81872-42-6)
• EPA Substance Registry System: 2-(2-phenyl-2H-1,2,3-triazol-4-yl)tetrahydrofuran-3,4-diol(81872-42-6)

Safety Data

• Hazardous Substances Data: 81872-42-6(Hazardous Substances Data)

Usage

Chemical class

1,2,3-triazoles

Structural features

Triazole ring, tetrahydrofuran ring, and phenyl group

Potential applications

Pharmaceutical research and drug development, materials science, and organic synthesis

Complexity

Complex structure

Molecular versatility

May interact with biological targets due to structural features

Need for further research

To fully understand its potential uses and properties.

Upstream product

• 15476-34-3 L_r-1cat_F-1-(2-phenyl-2H-[1,2,3]triazol-4-yl)-butane-1c_F,2t_F,3r_F,4-tetraol 
• 75869-76-0 L-lyxo-3,6-anhydro-[2]hexosulose-bis-phenylhydrazone 
• 35522-78-2 (3R,4S)-2-[1,2-Bis-(phenyl-hydrazono)-ethyl]-tetrahydro-furan-3,4-diol 

Downstream Products

• 95707-66-7 (3S)-2c-[2-(4-nitro-phenyl)-2H-[1,2,3]triazol-4-yl]-tetrahydro-furan-3r,4c-diol 
• 95707-66-7 (3R)-2t-[2-(4-nitro-phenyl)-2H-[1,2,3]triazol-4-yl]-tetrahydro-furan-3r,4t-diol 
• 99801-44-2 4-((3aS)-2,2-dimethyl-(3ar,6ac)-tetrahydro-furo[3,4-d][1,3]dioxol-4t-yl)-2-(4-nitro-phenyl)-2H-[1,2,3]triazole 
• 97832-39-8 (2S)-3c,4c-diacetoxy-2r-[2-(4-nitro-phenyl)-2H-[1,2,3]triazol-4-yl]-tetrahydro-furan 
• 107543-44-2 (2S)-2r-[2-(4-nitro-phenyl)-2H-[1,2,3]triazol-4-yl]-3t,4c-bis-(toluene-4-sulfonyloxy)-tetrahydro-furan 

Relevant articles and documents

STUDIES ON 3-EPIMERIC L-2-HEXULOSE PHENYLOSAZONES. STRUCTURE AND ANOMERIC CONFIGURATION OF THE 3,6-ANHYDRO-OSAZONE DERIVATIVES OBTAINED FROM L-xylo- AND L-lyxo-2-HEXULOSE PHENYLOSAZONE

Dehydration of the 3-epimeric 2-hexulose phenylosazones L-xylo-hexulose phenylosazone and L-lyxo-hexulose phenylosazone afforded 3,6-anhydro-L-lyxo-2-hexulose phenylosazone (2) as the preponderant isomer from both.The identity of 2 was obtained by t.l.c., and by acetylation followed by comparison of the products.Acetylation of 2 with acetic anhydride-pyridine afforded the di-O-acetyl derivative 4, and further acetylation gave the N-acetyl-di-O-acetyl derivative 5.Refluxing of 2 with copper sulfate afforded a C-nucleoside analog, namely, 2-phenyl-4-α-L-threo-furanosyl-1,2,3-osotriazole (6).The anomeric configuration was determined by n.m.r. spectroscopy.The stereochemical course of the dehydration process and the mass spectra of compounds 2, 4, 5, and 6 are discussed.