81907-62-2

Basic information

• Product Name: GANODERIC ACID A
• Synonyms: GANODERIC ACID A;(25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid;Aids070759;Aids-070759;Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7.beta.,15.alpha.,25R)-;(7beta,15alpha,25R)-7,15-Dihydroxy-3,11,23-trioxo-lanost-8-en-26-oic acid;GANODERIC ACID A(P);(25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oicaci
• CAS NO: 81907-62-2
• Molecular Formula: C30H42O7
• Molecular Weight: 514.65
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 81907-62-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 118～123℃
• Boiling Point: 690.1 °C at 760 mmHg
• Flash Point: 385.1 °C
• Appearance: /
• Density: 1.22
• Vapor Pressure: 4.89E-22mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• Solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly)
• PKA: 4.78±0.23(Predicted)
• CAS DataBase Reference: GANODERIC ACID A(CAS DataBase Reference)
• NIST Chemistry Reference: GANODERIC ACID A(81907-62-2)
• EPA Substance Registry System: GANODERIC ACID A(81907-62-2)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 81907-62-2(Hazardous Substances Data)

Usage

Description

Ganoderic Acid A is a lanostanoid triterpene extracted from the fruit bodies of Ganoderma Lucidum mushroom, which possesses diverse biological activities and therapeutic properties.

Uses

Used in Pharmaceutical Industry:
Ganoderic Acid A is used as an anti-viral, anti-inflammatory, anti-tumor, immunity-promoting, and anti-diabetic agent for its diverse therapeutic properties and ability to target various health conditions.
Used in Cancer Treatment:
Ganoderic Acid A is used as an anti-tumor agent for reducing cell viability, expression of superoxide dismutase enzymes, and production of reactive oxygen species in PC3 prostate cancer cells.
Used in Cardiovascular Protection:
Ganoderic Acid A is used as a cardioprotective agent for reducing hypoxia-induced apoptosis in H9c2 cardiomyocytes.
Used in Anti-Inflammatory Applications:
Ganoderic Acid A is used as an anti-inflammatory agent for inhibiting LPS-induced activation of NF-κB, release of pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6), and mitochondrial activity in primary mouse cortical microglia.
Used in Respiratory Disease Treatment:
Ganoderic Acid A is used as a therapeutic agent for reducing lung myeloperoxidase activity, neutrophil infiltration, NF-κB signaling, and bronchoalveolar lavage fluid levels of pro-inflammatory cytokines in a mouse model of LPS-induced lung injury.
Used in Obesity and Metabolic Syndrome Management:
Ganoderic Acid A is used as a weight management and insulin sensitivity improving agent for reducing weight gain, hepatic lipid accumulation, and improving insulin sensitivity in a mouse model of high-fat diet-induced obesity.
Chemical Properties:
Ganoderic Acid A is a white powder.

InChI:InChI=1/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,23,32,35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,23+,28+,29-,30+/m1/s1