81963-12-4

Basic information

• Product Name: 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo<3,2-ij>quinoline-5-carboxylic acid
• CAS NO: 81963-12-4
• Molecular Weight: 265.216
• Mol File: 81963-12-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo<3,2-ij>quinoline-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo<3,2-ij>quinoline-5-carboxylic acid(81963-12-4)
• EPA Substance Registry System: 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo<3,2-ij>quinoline-5-carboxylic acid(81963-12-4)

Safety Data

• Hazardous Substances Data: 81963-12-4(Hazardous Substances Data)

Upstream product

• 3863-11-4 3,4-difluoroaniline 
• 132142-65-5 7-Bromo-3-ethylthio-4,5-difluoro-2-methylindole 
• 85462-60-8 4,5-Difluoro-2-methylindole 
• 64695-79-0 2-bromo-4,5-difluoro-aniline 
• 121247-19-6 <<(3,4-difluoro-2-(2-hydroxypropyl)phenyl)amino>methylene>propanedioic acid diethyl ester 
• 121247-20-9 <(4,5-difluoro-2,3-dihydro-2-methyl-1H-indol-1-yl)methylene>propanedioic acid diethyl ester 
• 121247-16-3 1-(2,3-difluoro-6-nitrophenyl)propan-2-one 
• 121247-17-4 3,4-difluoro-2-(2-hydroxypropyl)nitrobenzene 
• 121247-18-5 3,4-difluoro-2-(2-hydroxypropyl)aniline 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 85730-59-2 4,5-difluoro-2-methyl-2,3-dihydro-1H-indole 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 85730-60-5 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo<3,2-ij>quinoline-5-carboxylic acid ethyl ester 

Relevant articles and documents

Studies on antibacterial agents. II. Synthesis and antibacterial activities of substituted 1,2-dihydro-6-oxo-6H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acids

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Synthesis of 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo[3,2,1-ij]quinoline-5-c arboxylic acid

A new and efficient seven-step synthesis of 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo[3,2,1-ij]-quinoline-5- carboxylic acid (9), an important intermediate used in the synthesis of quinolone antibacterials, has been developed beginning with commercia