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81965-43-7

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81965-43-7 Usage

Purpose

Used in chemotherapy for the treatment of malignant brain tumors

Classification

Nitrosourea alkylating agent

Mechanism of action

Crosses the blood-brain barrier and inhibits cancer cell growth by damaging their DNA

Administration

Typically administered orally

Absorption

Well absorbed in the gastrointestinal tract

Half-life

Long, allowing for prolonged exposure to cancer cells

Side effects

Can cause serious side effects such as bone marrow suppression, liver toxicity, and pulmonary fibrosis

Prescription guidelines

Only prescribed by oncologists with expertise in its administration and monitoring of adverse effects

Check Digit Verification of cas no

The CAS Registry Mumber 81965-43-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,9,6 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81965-43:
(7*8)+(6*1)+(5*9)+(4*6)+(3*5)+(2*4)+(1*3)=157
157 % 10 = 7
So 81965-43-7 is a valid CAS Registry Number.

81965-43-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[[2-chloroethyl(nitroso)carbamoyl]-methylamino]acetamide

1.2 Other means of identification

Product number -
Other names Sarcosinamide chloroethylnitrosourea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81965-43-7 SDS

81965-43-7Downstream Products

81965-43-7Relevant articles and documents

(2-Chloroethyl)nitrosourea congeners of amino acid amides

Suami,Kato,Takino,Hisamatsu

, p. 829 - 832 (1982)

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