820212-25-7Relevant articles and documents
Efficient synthesis of nucleoside aryloxy phosphoramidate prodrugs utilizing benzyloxycarbonyl protection
Cho, Jong Hyun,Amblard, Franck,Coats, Steven J.,Schinazi, Raymond F.
, p. 5487 - 5493 (2011/08/06)
An efficient method for the synthesis of nucleoside phosphoramidates prodrugs (6a-f) has been developed that employs a simple protection/deprotection sequence of the nucleoside with benzyloxycarbonyl (Cbz). The coupling reaction of Cbz-protected derivativ