82044-12-0

Basic information

• Product Name: 1-{1-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-2-phenyl-ethanone
• CAS NO: 82044-12-0
• Molecular Weight: 459.542
• Mol File: 82044-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{1-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-2-phenyl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{1-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-2-phenyl-ethanone(82044-12-0)
• EPA Substance Registry System: 1-{1-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-2-phenyl-ethanone(82044-12-0)

Safety Data

• Hazardous Substances Data: 82044-12-0(Hazardous Substances Data)

Upstream product

• 1555-80-2 phenylacetic anhydride 
• 6957-27-3 3,4-dihydropapaverine 

Relevant articles and documents

Reaction of Isoquinoline Enamides with Electrophiles

The reaction of isoquinoline enamides with acyl isocyanates yields vinylogous amides through carbon-carbon bond formation between the β carbon of the enamide and the isocyanate carbonyl.Enamide formation occurs between 1-benzyl-3,4-dihydroisoquinolines and phenylacetic anhydride.However, a N,C-bis(phenylacetyl) derivative is formed with phenylacetyl chloride.The reaction occurs through preferential reaction of phenylketene with the enamine tautomer of the 1-benzyl-3,4-dihydroisoquinoline at the carbon terminus, followed by N-acylation.The equilibrium is demonstrated by deuterium NMR.