82045-10-1

Basic information

• Product Name: trans-2,2-Difluoro-3-phenylcyclopropan-1-carbonsaeure-methylester
• Synonyms: trans-2,2-Difluoro-3-phenylcyclopropan-1-carbonsaeure-methylester
• CAS NO: 82045-10-1
• Molecular Weight: 212.196
• Mol File: 82045-10-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: trans-2,2-Difluoro-3-phenylcyclopropan-1-carbonsaeure-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: trans-2,2-Difluoro-3-phenylcyclopropan-1-carbonsaeure-methylester(82045-10-1)
• EPA Substance Registry System: trans-2,2-Difluoro-3-phenylcyclopropan-1-carbonsaeure-methylester(82045-10-1)

Safety Data

• Hazardous Substances Data: 82045-10-1(Hazardous Substances Data)

Upstream product

• 103-26-4 Methyl cinnamate 
• 24925-18-6 phenyl(trifluoromethyl)mercury 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 103-26-4 methyl cinnamate 
• 82045-06-5 1-(acetoxymethyl)-2,2-difluoro-3-phenylcyclopropane 
• 118138-22-0 trans-(+/-)-(2,2-difluoro-3-phenylcyclopropyl)methanol 
• 21040-45-9 Cinnamyl acetate 
• 186581-53-3 diazomethane 
• 82045-18-9 trans-(+/-)-2,2-difluoro-3-phenylcyclopropane-1-carboxylic acid 

Downstream Products

• 15463-92-0 dimethyl 2-phenylsuccinate 

Relevant articles and documents

Fluoro Analoga of Cycloheptadiene Pheromones of Marine Brown Algae: Exceptionally Facile -Sigmatropic Rearrangement of a trans-Di(alkyl)-Substituted Geminal Difluorocyclopropane

The 3,3-difluorocyclopropane-1,2-dicarbonyl compounds 9a and 9b are obtained by addition of difluorocarbene to methyl cinnamate or trans-stilbene followed by oxidative degradation of the phenyl rings(s) (Scheme 2).Compound 9b is a versatile building block

Studies on Organic Fluorine Compounds. 38. Ring-Opening Reactions of gem-Difluorocyclopropyl Ketones with Nucleophiles

Syntheses of gem-difluorocyclopropyl ketones (3a-d) and their reactions with nucleophiles are described.Ring-opening reaction of 3a,c,d having a hydrogen substituent at C1 adjacent to the carbonyl group with a methanolate anion gave carboxylic acid derivatives derived from C1-C2 bond scission (between the carbon atom with an acyl group and the carbon atom with fluorine substituents).On the other hand, reaction of 3a-c with a thiolate anion resulted in the C1-C3 bond cleavage (carbon-carbon bond opposite to the difluoromethylene group).