82068-55-1

Basic information

• Product Name: L-Methioninamide, N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-
• CAS NO: 82068-55-1
• Molecular Formula: C36H53N7O6S
• Molecular Weight: 711.926
• Mol File: 82068-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Methioninamide, N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Methioninamide, N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-(82068-55-1)
• EPA Substance Registry System: L-Methioninamide, N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-(82068-55-1)

Safety Data

• Hazardous Substances Data: 82068-55-1(Hazardous Substances Data)

Upstream product

• 27219-07-4 5-(N-tert-butyloxycarbonyl)aminopentanoic acid 
• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 
• 35661-40-6 N-Fmoc L-Phe 

Relevant articles and documents

Conformationally Constrained Tachykinin Analogues: Potent and Highly Selective Neurokinin NK-2 Receptor Agonists

The design and synthesis of potent and selective neurokinin NK-2 receptor agonists 12 (GR64349) and 31 are described, together with structure-activity relationships for related analogues.Compound 12 (EC50 = 3.7 nM at NK-2 receptors in the rat colon; selectivity >1000- and >300-fold with respect to NK-1 and NK-3 receptors, respectively) was derived by incorporation of a Gly-Leu γ-lactam conformational constraint into the C-terminal region of the neurokinin A octapeptide analogue 3>-NKA(3-10).Compound 31 (EC50 = 15 nM in rat colon) contains a novel fused-bicyclicconstraint at the corresponding site in the substance P hexapeptide analogue 6>-SP(6-11).