82093-34-3

Basic information

• Product Name: tetrahydro-1H-cyclopenta[c]furan-1,4(3H)-dione
• Synonyms: 1H-cyclopenta[c]furan-1,4(3H)-dione, tetrahydro-; Tetrahydro-1H-cyclopenta[c]furan-1,4(3H)-dione
• CAS NO: 82093-34-3
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.1366
• Mol File: 82093-34-3.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 343.4°C at 760 mmHg
• Flash Point: 158.1°C
• Density: 1.309g/cm³
• Vapor Pressure: 7.06E-05mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: tetrahydro-1H-cyclopenta[c]furan-1,4(3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: tetrahydro-1H-cyclopenta[c]furan-1,4(3H)-dione(82093-34-3)
• EPA Substance Registry System: tetrahydro-1H-cyclopenta[c]furan-1,4(3H)-dione(82093-34-3)

Safety Data

• Hazardous Substances Data: 82093-34-3(Hazardous Substances Data)

Upstream product

• 87701-83-5 3-oxabicyclooctenone 
• 82134-77-8 (3aR,6aS)-1-Hydroxy-hexahydro-cyclopenta[c]furan-4-one 
• 82093-33-2 C₉H₁₂O₄ 
• 77189-14-1 1-oxo-1,3,3a,6a-tetrahydrocyclopentafuran 
• 94530-31-1 5-Cyano-cyclopent-1-enecarboxylic acid methyl ester 
• 94530-32-2 2-Cyano-5-ethylsulfanyl-cyclopentanecarboxylic acid methyl ester 
• 94530-30-0 1-Cyano-cyclopent-2-ene-1,2-dicarboxylic acid dimethyl ester 
• 68882-71-3 2-(hydroxymethyl)cyclopent-2-enone 
• 82134-76-7 3-vinyl-2-(hydroxymethyl)cyclopentanone 
• 82093-31-0 2-(hydroxymethylene)-3-cyanocyclopentanone ethylene ketal 
• 73982-07-7 7-Cyano-1,4-dioxa-spiro[4.4]nonane-6-carboxylic acid methyl ester 

Downstream Products

• 72581-31-8 sarkomycin 

Relevant articles and documents

Sarkomycin a methyl esters and functionalized cyclopentane blocks for brefeldin a

Sarkomycin A methyl esters and functionalized cyclopentane blocks for brefeldin A were synthesized starting from diastereoisomeric (1R,2S)-and (1S,2R)-2-hydroxymethyl-N-[(1R)-1-phenylethyl]cyclopent-3-ene-1-carboxamides. Pleiades Publishing, Ltd., 2012.

An integrated chemoenzymatic synthesis of enantiopure (-)-(1R,5S)-cyclosarkomycin: A sarkomycin precursor

A five-step chemoenzymatic synthesis of (-)-(1R,5S)-cyclosarkomycin 2 has been achieved starting from commercial racemic bicycloheptenone 3. The strategy developed involved - as key steps - an enantioselective microbiologically catalyzed Baeyer-Villiger oxidation followed by a chemical regioselective epoxide ring opening.

DIASTEREOSELECTIVE IODOCARBOCYCLIZATION OF 4-PENTENYLMALONATE DERIVATIVES: APPLICATION TO CYCLOSARKOMYCIN SYNTHESIS

The iodocarbocyclization of 4-pentenylmalonate 1 having a substituent at the 2 or 3 position effectively proceeded by treating 1 with I2 and Ti(OtBu)4 in the presence of CuO.Stereoelectronic effect of the substituent at allylic position on diastereoselect