82100-78-5Relevant articles and documents
Sodium carbonate-mediated facile synthesis of 4-substituted-2-(3,5- dimethylpyrazol-1-yl)thiazoles under solvent-free conditions
Aggarwal, Ranjana,Kumar, Sunil,Singh, Shiv P.
, p. 521 - 525,5 (2020/09/16)
An efficient and facile synthesis of 4-substituted-2-(3,5-dimethylpyrazol- 1-yl)thiazoles 3 was achieved by grinding an equimolar mixture of -haloketones 2 with 3,5-dimethylpyrazol-1-thiocarboxamide 1 in the presence of sodium carbonate under the solvent-
A facile one-pot synthesis of 2-pyrazolyl-4-aryl-thiazoles in a threecomponent reaction
Nalajam, Guravaiah,Vedula, Rajeswar Rao
experimental part, p. 195 - 197 (2009/08/07)
A one-pot multi-component reaction of phenacylbromide, thiosemicarbazide and acetyl acetone or ethyl acetoacetate is described for the preparation of the title compounds. The key features of this methodology are its operational simplicity, mild reaction conditions, and good yields.
Unexpected Formation of α-Thiocyanatoketones in Hantzsch Thiazole Synthesis
Singh, S. P.,Sehgal, Subhash,Singh, Lukhvinder,Dhawan, S. N.
, p. 154 - 155 (2007/10/02)
The reaction of 3,5-dimethylpyrazole-1-thiocarboxamide (3) with α-haloketones (4) yields the corresponding α-thiocyanatoketones (5) or pyrazoles (1) depending upon nature of the halogen.Many such pyrazole derivatives have erroneously been described as thiazolotriazepines in literature.