82122-53-0

Basic information

• Product Name: 3-methyl-[5']thymidylic acid
• Synonyms: 3-methyl-[5']thymidylic acid
• CAS NO: 82122-53-0
• Molecular Weight: 336.238
• Mol File: 82122-53-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-[5']thymidylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-[5']thymidylic acid(82122-53-0)
• EPA Substance Registry System: 3-methyl-[5']thymidylic acid(82122-53-0)

Safety Data

• Hazardous Substances Data: 82122-53-0(Hazardous Substances Data)

Upstream product

• 512-56-1 trimethyl phosphite 
• 365-07-1 thymidine 5'-phosphate 

Relevant articles and documents

METHYLATION OF DEOXYNUCLEOTIDES WITH TRIMETHYL PHOSPHATE IN AQUEOUS PHASE.

Action of trimethyl phosphate on thymidine 5 prime -phosphate, deoxycytidine 5 prime -phosphate, deoxyadenosine 5 prime -phosphate, and deoxyguanosine 5 prime -phosphate at 37-60 degree C, and pH 7-10 gave their methyl esters and base-methylated derivatives. Esterification took place in all deoxyribonucleotides to the almost same extent and its rate was enhanced by the reaction temperature, while being independent of pH in the range 7-10. On the other hand, methylation of the base moieties was affected by both the reaction temperature and pH of the reaction medium.