82130-73-2

Basic information

• Product Name: Butanedioic acid, (phenylmethoxy)-, dimethyl ester, (2S)-
• CAS NO: 82130-73-2
• Molecular Formula: C13H16O5
• Molecular Weight: 252.267
• Mol File: 82130-73-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Butanedioic acid, (phenylmethoxy)-, dimethyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, (phenylmethoxy)-, dimethyl ester, (2S)-(82130-73-2)
• EPA Substance Registry System: Butanedioic acid, (phenylmethoxy)-, dimethyl ester, (2S)-(82130-73-2)

Safety Data

• Hazardous Substances Data: 82130-73-2(Hazardous Substances Data)

Upstream product

• 617-55-0 dimethyl (S)-malate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 100-39-0 benzyl bromide 
• 134356-95-9 dimethyl 2-(benzyloxy)succinate 
• 100-51-6 benzyl alcohol 
• 38115-87-6 malic acid dimethyl ester 

Downstream Products

• 129151-77-5 (S)-methyl 3-(benzyloxy)-4-oxobutanoate 
• 82130-74-3 (S)-3-Benzyloxy-dihydro-furan-2,5-dione 
• 134298-54-7 (S)-2-Benzyloxy-succinic acid 4-methyl ester 
• 101999-38-6 (S)-4-benzyloxy-dihydrofuran-2(3H)-one 
• 872130-28-4 (S)-4-Benzyloxy-tetrahydro-furan-2-ol 
• 82130-79-8 3-((S)-4-Benzyloxy-tetrahydro-furan-2-yloxy)-2,2-dimethyl-propan-1-ol 
• 82130-78-7 (S)-2-benzyloxy-3-(5,5-dimethyl-1,3-dioxan-2-yl)propan-1-ol 
• 82130-81-2 2-((S)-2-Benzyloxy-3-iodo-propyl)-5,5-dimethyl-[1,3]dioxane 
• 82130-85-6 2-((S)-2-Benzyloxy-but-3-ynyl)-5,5-dimethyl-[1,3]dioxane 
• 82130-82-3 2-((S)-4-Benzenesulfinyl-2-benzyloxy-4-chloro-butyl)-5,5-dimethyl-[1,3]dioxane 
• 82130-80-1 Toluene-4-sulfonic acid (S)-2-benzyloxy-3-(5,5-dimethyl-[1,3]dioxan-2-yl)-propyl ester 
• 82130-83-4 2-((E)-(S)-2-Benzyloxy-4-chloro-but-3-enyl)-5,5-dimethyl-[1,3]dioxane 
• 129151-79-7 methyl (3S,4S)-4-hydroxy-3-(phenylmethoxy)hept-6-enoate 
• 129151-78-6 (3S,4R)-3-Benzyloxy-4-hydroxy-hex-5-enoic acid methyl ester 

Relevant articles and documents

Preparation method of (S)-3-hydroxytetrahydrofuran

The invention discloses a preparation method of (S)-3-hydroxytetrahydrofuran. The problems that butantriol is difficult to separate in the production process, the yield is not high and the impurity content and the isomer content of the products are high are mainly solved. The preparation method of (S)-3-hydroxytetrahydrofuran comprises the following steps: under the existence of sulfoxide chloride, malic acid reacts with methanol to generate a compound II; under the existence of silver oxide, performing reaction on the compound II and benzyl bromide to generate a compound III; reducing the compound III by sodium borohydride to generate a compound IV; performing dehydration and ring closing on the compound IV by p-toluenesulfonic acid to generate a compound V; and taking palladium carbon asa catalyst and performing hydrogen reduction treatment on the compound V to obtain the product. The method is simple in aftertreatment and environment-friendly; the yield of the products is increasedby 80 percent or more, the purity is more than 99.5 percent and the chiral purity is more than 99.2 percent; and the method is suitable for industrialized production. (The formulas are as shown in the description).

Design and concise synthesis of gem-difluoromethylenated analogue of 7-epi-castanospermine

A novel gem-difluoromethylenated castanospermine analogue B was designed and synthesized, starting from 3-bromo-3,3-difluoropropene and L-(-)-malic acid. The key steps involve substitution cyclization reaction and RCM reaction to construct the aza fused b

A chiral pool based approach to antipodes of α-cuparenone

A synthetic route to both antipodes of α-cuparenone was achieved from the readily available chiral pool starting material l-malic acid and involved cyclopentannulation as the key step.