82212-14-4

Basic information

• Product Name: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide
• Synonyms: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide;-AMINO-2-CHLORO-5-(1H-TETRAZOLE-5YL)BENZENESULFONAMIDE(U);4-Amino-2-Chloro-5-(1H-Tetrazole-5-yl)Benzenesulfonamide;4-AMINO-2-CHLORO-5-(1 H-TETRAZOLE-5 YL)BENZENESULFONAMIDE (U);4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide;5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole;Einecs 279-922-2;5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole
• CAS NO: 82212-14-4
• Molecular Formula: C7H7ClN6O2S
• Molecular Weight: 274.68748
• EINECS: 279-922-2
• Mol File: 82212-14-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 633.871 °C at 760 mmHg
• Flash Point: 337.153 °C
• Appearance: /
• Density: 1.762 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.691
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Dimethylformamide
• PKA: 3.40±0.10(Predicted)
• CAS DataBase Reference: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide(82212-14-4)
• EPA Substance Registry System: 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide(82212-14-4)

Safety Data

• Hazardous Substances Data: 82212-14-4(Hazardous Substances Data)

Usage

General Description

2-Chloro-5-(1H-tetrazol-5-yl)sulphanilamide is a chemical compound characterized by its tetrazol group, sulphanilamide moiety, and a chlorine atom. 2-chloro-5-(1H-tetrazol-5-yl)sulphanilamide contributes to the area of organic chemistry and is considered to have important bioactivity. Its structure is a combination of multiple rings, including a tetrazole and a sulfonamide group, and has specific roles in molecular development. However, detailed properties about its physical state, toxicity, industrial applications, or bioactivity have not been extensively reported. Its synthesis can be achieved in a lab setting, but safety precautions must be taken due to the relative reactivity of some of its constituent groups.

InChI:InChI=1/C7H7ClN6O2S/c8-4-2-5(9)3(7-11-13-14-12-7)1-6(4)17(10,15)16/h1-2H,9H2,(H2,10,15,16)(H,11,12,13,14)

Upstream product

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Relevant articles and documents

Azosemide intermediate synthesizing method

The invention discloses an azosemide intermediate synthesizing method. The method comprises the steps of performing tetrazole reaction to prepare a compound A: warming and enabling 4-chlorin-2-nitro benzonitrile and sodium azide to react under action of a catalyst and extracting reaction liquid by water to obtain reaction liquid of the compound A; directly performing hydrogenation reaction to prepare a compound B; performing chlorosulfonation reaction to prepare a compound C: slowly dropping qualified compound B and chlorosulfonic acid into cold water after temperature reaction and center control qualification, extracting through an organic solvent, standing for layering and decompressing, evaporating and drying the solvent in an organic phase mode to obtain a compound crude product C; performing ammonolysis reaction to prepare a compound D. Compared with the prior art, raw materials of the method disclosed by the invention are easy to obtain and low in cost; the method is low in cost, convenient to operate, suitable for industrialization and little in generated three wastes; furthermore, comprehensive utilization of waste can meet national industrial policy.