82212-55-3

Basic information

• Product Name: Pentanenitrile, 2-amino-2-(fluoromethyl)-5-(phenylmethoxy)-
• CAS NO: 82212-55-3
• Molecular Formula: C13H17FN2O
• Molecular Weight: 236.289
• Mol File: 82212-55-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pentanenitrile, 2-amino-2-(fluoromethyl)-5-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanenitrile, 2-amino-2-(fluoromethyl)-5-(phenylmethoxy)-(82212-55-3)
• EPA Substance Registry System: Pentanenitrile, 2-amino-2-(fluoromethyl)-5-(phenylmethoxy)-(82212-55-3)

Safety Data

• Hazardous Substances Data: 82212-55-3(Hazardous Substances Data)

Upstream product

• 453-15-6 fluoroacetonitrile 
• 26420-79-1 1-chloro-3-benzyloxypropane 
• 503-20-8 fluoroacetonitrile 
• 74-88-4 methyl iodide 

Downstream Products

• 82212-56-4 2-fluoromethyl-2-phthalimido-5-benzyloxy-valeronitrile 

Relevant articles and documents

2-(4-Amino-4-carboxybutyl)aziridine-2-carboxylic acid. A potent irreversible inhibitor of diaminopimelic acid epimerase. Spontaneous formation from α-(halomethyl)diaminopimelic acids

2-(4-Amino-4-carboxybutyl)aziridine-2-carboxylic acid (3) (aziridino-DAP) was identified as the product of spontaneous hydrolysis of α-(halomethyl)diaminopimelic acids (α-halomethyl-DAPs) 2a-c. Under physiological conditions, 3 is an extremely potent irre

Process for preparing fluorinated amino-nitriles

Certain α-(fluoromethyl or difluoromethyl)-α-aminoacetonitriles are prepared by treating the appropriate α-(fluoromethyl or difluoromethyl) ketimine magnesium halide with hydrogen cyanide or with an alkali metal cyanide or ammonium cyanide and a proton source. The products are useful as intermediates for making α-(fluoromethyl or difluoromethyl)-α-amino acids having pharmacological activity.