82222-48-8

Basic information

• Product Name: 2-(4-Phenyl-thiazol-2-yl)-benzo[f]chromen-3-one
• Synonyms: 2-(4-Phenyl-thiazol-2-yl)-benzo[f]chromen-3-one
• CAS NO: 82222-48-8
• Molecular Weight: 355.417
• Mol File: 82222-48-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-Phenyl-thiazol-2-yl)-benzo[f]chromen-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Phenyl-thiazol-2-yl)-benzo[f]chromen-3-one(82222-48-8)
• EPA Substance Registry System: 2-(4-Phenyl-thiazol-2-yl)-benzo[f]chromen-3-one(82222-48-8)

Safety Data

• Hazardous Substances Data: 82222-48-8(Hazardous Substances Data)

Upstream product

• 135-19-3 β-naphthol 
• 70-11-1 α-bromoacetophenone 
• 69015-72-1 3-oxo-3H-benzo[f]chromene-2-carbothioic acid amide 
• 134835-13-5 1-<(4'-nitrophenylimino)methyl>-2-naphthol 
• 41381-89-9 2-(4-phenylthiazol-2-yl)acetonitrile 

Relevant articles and documents

Ensembles of rings with a coumarin unit. 1. Synthesis of 3-(2-R-thiazol-4-yl)- and 3-(4-R-triazol-2-yl)coumarins

We have synthesized 3-(2-R-thiazol-4-yl)coumarins (R = H, CH3, CH2CN, Ar) by condensation of 3-(α-bromoacetyl)coumarins with thioamides. We obtained 3-(4-R-thiazol-2-yl)coumarins (R = H, Ar) by several methods. By reaction of 2-cyanomethyl-4-phenylthiazole with 2-hydroxybenzaldehydes, we synthesized 2-imino-3-(4-phenylthiazol-2-yl)coumarins, which were converted to the corresponding coumarins by acid hydrolysis. For 3-(2-R-thiazol-4-yl)coumarins (R = CH2CN), we carried out reactions with aromatic aldehydes. We propose alternative methods for synthesis of 2-[2-aryl(hetaryl)-1-cyanoethenyl]-4-(coumarin-3-yl)thiazoles. 1998 Plenum Publishing Corporation.