82255-69-4

Basic information

• Product Name: 3(2H)-Isoquinolinone, 4-methyl-1-phenyl-
• CAS NO: 82255-69-4
• Molecular Formula: C16H13NO
• Molecular Weight: 235.285
• Mol File: 82255-69-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3(2H)-Isoquinolinone, 4-methyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Isoquinolinone, 4-methyl-1-phenyl-(82255-69-4)
• EPA Substance Registry System: 3(2H)-Isoquinolinone, 4-methyl-1-phenyl-(82255-69-4)

Safety Data

• Hazardous Substances Data: 82255-69-4(Hazardous Substances Data)

Upstream product

• 17507-05-0 1-phenyl-1,4-dihydro-3(2H)-isoquinolinone 
• 68-12-2 N,N-dimethyl-formamide 
• 462-80-6 benzyne 
• 142128-23-2 (S,E)-ethyl 2-(benzylideneamino)propanoate 
• 140-29-4 phenylacetonitrile 
• 82255-73-0 1-Phenyl-1,4-dihydro-3-(2H)isoquinolinone-1-d 
• 40119-31-1 1-Phenyl-4-methyl-1,4-dihydro-3-(2H)isoquinolinone 
• 50-00-0 formaldehyd 

Downstream Products

• 87748-06-9 C₂₆H₂₀N₂O₃ 
• 87748-06-9 C₂₆H₂₀N₂O₃ 
• 95849-62-0 C₂₀H₁₆N₂O₃ 
• 87748-22-9 C₂₀H₁₅NO₄ 
• 87748-22-9 C₂₀H₁₅NO₄ 
• 105504-32-3 C₃₂H₂₆N₂O₇ 
• 105479-14-9 (Z)-2-(4-Methyl-3-oxo-1-phenyl-3H-isoquinolin-2-yl)-but-2-enedioic acid dimethyl ester 
• 93098-35-2 3-allyloxy-1-phenyl-4-methylisoquinoline 
• 93098-36-3 1-phenyl-3-methanesulphonyloxy-4-methylisoquinoline 
• 121409-97-0 1-phenyl-4-methyl-5,6,7,8-tetrahydro-3(2H)-isoquinolinone 
• 40119-31-1 cis-1-phenyl-4-methyl-1,4-dihydro-3(2H)-isoquinolinone 
• 95849-61-9 C₂₁H₁₇N₃O₄ 

Relevant articles and documents

Competitive 3+2 and 2+2 cycloadditions of ester stabilized azaallyl anions to benzynes. Ring expansion of initial 3+2 products to isoquinolin-3-ones

Reaction of the azaallyllithiums derived from imines of α-amino esters with benzynes results in the formation of 1,3-dihydroisoindoles and 4-hydroxyisoquinolines via 3+2 and 2+2 cycloadditions, respectively. The initially formed 1-carboethoxy-1,3-dihydroisoindoles rearrange under basic reaction conditions to form 3-(2H)-isoquinolinones.

Reactions of 1,4-Dihydro-3-(2H)benzoisoquinolinones with Aldehydes in the Presence of a Strong Base. Condensation and Aromatization as Competing Reactions

In reactions of 1-phenyl-1,4-dihydro-3-(2H)benzoisoquinolinones with benzaldehyde in the presence of a strong base, the final result can be ring substitution with aromatization or only aromatization of the starting isoquinolinone, depending on the positio