82267-02-5Relevant articles and documents
COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF AS INHIBITORS OF RAN GTPASE
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Paragraph 0071; 0076; 0091; 0092, (2019/04/09)
Compounds of general formula IA, IB and IC outlined below, including pharmaceutically acceptable salts, solvates and hydrates thereof. Such compounds and pharmaceutical compositions comprising them may be used in medical conditions involving Ran GTPase.
Synthesis of novel C4-linked C2-imidazole ribonucleoside phosphoramidite and its application to probing the catalytic mechanism of a ribozyme
Araki, Lisa,Morita, Keiji,Yamaguchi, Maho,Zhao, Zheng-Yun,Wilson, Timothy J.,Lilley, David M. J.,Harusawa, Shinya
supporting information; experimental part, p. 2350 - 2356 (2009/07/25)
The synthesis of a novel C4-linked C2-imidazole ribonucleoside phosphoramidite (ICN-C2-PA 1) with a two-carbon linker between imidazole and ribose moieties is described. In the phosphoramidite, POM and 2-cyanoethyl groups were select
Synthesis of C-Nucleosides via Radical Coupling Reaction
Togo, Hideo,Ishigami, Sachiko,Fujii, Misa,Ikuma, Toshihiro,Yokoyama, Masataka
, p. 2931 - 2942 (2007/10/02)
Photolysis of O-acyl derivatives of N-hydroxy-2-thiopyridone, prepared from tetrahydrofuran-2-carboxylic acid, D-ribofuranosylmethanoic acid, and D-ribopyranosylmethanoic acid, gave the corresponding C-nucleoside derivatives in the presence of heteroaromatic compounds via radical pathways.The essential step in this method is a radical coupling reaction of D-ribofuranosyl radical or D-ribopyranosyl radical and some heteroaromatic bases.This is a new method for the preparation of C-nucleosides using sugar carboxylic acids.