823221-48-3

Basic information

• Product Name: 1-benzyl-6-methylamino-5-formylaminouracil
• Synonyms: 1-benzyl-6-methylamino-5-formylaminouracil
• CAS NO: 823221-48-3
• Molecular Weight: 274.279
• Mol File: 823221-48-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-6-methylamino-5-formylaminouracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-6-methylamino-5-formylaminouracil(823221-48-3)
• EPA Substance Registry System: 1-benzyl-6-methylamino-5-formylaminouracil(823221-48-3)

Safety Data

• Hazardous Substances Data: 823221-48-3(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 823221-47-2 6-(methylamino)-1-benzyl-5-nitrosouracil 
• 823221-46-1 1-benzyl-6-methylaminouracil 
• 124218-96-8 1-benzyl-6-chloropyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

6-Aminouracils as precursors for the syntheses of fused di- and tricyclic

The treatment of 1-benzyl-, or 1-methyl-6-chlorouracil (1a,b) with nucleophilic primary amines followed by nitrosation, reduction, formylation and dehydro-cyclisation lead to xanthines 5 and 7. While, the treatment of uracil 8 with aromatic aldehydes 9a-f leads to the formation of dipyrimidinopyridines 10a-f, reaction with formalin and primary amines gives pyrimidopyrimidines 11a-d via double Michael reactions.