82345-35-5

Basic information

• Product Name: 7β,8-Epoxy-11α,14-dihydroxy-12-oxo-3β,2α-[[(2S,3S,4R,6R)-tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]carda-4,20(22)-dienolide
• Synonyms: 7β,8-Epoxy-11α,14-dihydroxy-12-oxo-3β,2α-[[(2S,3S,4R,6R)-tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]carda-4,20(22)-dienolide;Affinoside A
• CAS NO: 82345-35-5
• Molecular Formula: C30H38O11
• Molecular Weight: 574.62
• Mol File: 82345-35-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 805°C at 760 mmHg
• Flash Point: 265.2°C
• Appearance: /
• Density: 1.49g/cm³
• Vapor Pressure: 5.53E-30mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 7β,8-Epoxy-11α,14-dihydroxy-12-oxo-3β,2α-[[(2S,3S,4R,6R)-tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]carda-4,20(22)-dienolide(CAS DataBase Reference)
• NIST Chemistry Reference: 7β,8-Epoxy-11α,14-dihydroxy-12-oxo-3β,2α-[[(2S,3S,4R,6R)-tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]carda-4,20(22)-dienolide(82345-35-5)
• EPA Substance Registry System: 7β,8-Epoxy-11α,14-dihydroxy-12-oxo-3β,2α-[[(2S,3S,4R,6R)-tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]carda-4,20(22)-dienolide(82345-35-5)

Safety Data

• Hazardous Substances Data: 82345-35-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C30H38O11/c1-13-7-20(36-4)30(35)25(38-13)39-17-9-15-10-19-29(41-19)23(26(15,2)11-18(17)40-30)22(32)24(33)27(3)16(5-6-28(27,29)34)14-8-21(31)37-12-14/h8-9,13,16-20,22-23,25,32,34-35H,5-7,10-12H2,1-4H3

Upstream product

• 104719-98-4 affinoside H 

Relevant articles and documents

Affinoside A and Companion Glycosides from the Stem and Bark of Anodendron affine (Anodendron II)

Cardenolide glycosides, affinosides A, C, D, E, F, G, H and J, were isolated from the stem and bark of Anodendron affine DRUCE, and their structures were elucidated.They have the same sugar moiety as affinoside B, 4,6-dideoxy-3-O-methyl-D-glycero-D-glycero-2-hexosulopyranose, which is doubly linked to the 2α- and 3β-hydroxyl groups of the aglycone with 2'-acetal and 1'-anomeric hydroxyl groups, respectively.The aglycone of A was identified as 2α,3β,11α,14-terahydroxy-12-oxo-14β-carda-4,20(22)-dienolide-7β,8β-epoxide.The others were found to be 2α,3β,14-trihydroxy-11-oxo-, 2α,3β,12α,14-tetrahydroxy-11-oxo-, and 2α,3β,5,12α,14-pentahydroxy-11-oxo-5β,14β-card-20(22)-enolide (C, E, and G, respectively), and 2α,3β,12β,14-tetrahydroxy-11-oxo-14β-carda-4,20(22)-dienolide (F).H, D, and J were Δ16-derivatives of A, C, and F, respectively.C was hydrolyzed to the aglycone by preliminary splitting of the 2-O-2' linkage by NaBH4 reduction, followed by treatment with HCl/acetone.Keywords---Anodendron; Apocynaceae; cardenolide; cardiac glycoside; affinoside; 3'-O-methyl-4',6'-dideoxy-2'-hexosulopyranoside; doubly linked cardenolide glycoside; 11-oxo-cardenolide; 12-oxo-cardenolide; 7,8-epoxy-cardenolide