82408-01-3Relevant articles and documents
ZnS nanoparticles as an efficient recyclable heterogeneous catalyst for one-pot synthesis of 4-substituted-1,5-benzodiazepines
Naeimi, Hossein,Foroughi, Hossein
, p. 1228 - 1236 (2015)
An efficient and novel method was developed for the synthesis of 4-substituted-1,5-benzodiazepine derivatives via a one-pot three-component catalytic reaction. The o-phenylenediamine and dimedone were reacted with aldehyde derivatives in the presence of ZnS nanoparticles as a heterogeneous catalyst under thermal conditions. The reaction was completed with high to excellent product yields and short reaction times. Simplicity of operation, high yields, easy work-up, easily accessible catalyst and purification of products through a crystallization method (non-chromatographic) are the key advantages of this work.
A nickel nanoparticle engineered CoFe2O4@GO-Kryptofix 22 composite: A green and retrievable catalytic system for the synthesis of 1,4-benzodiazepines in water
Mozafari, Roya,Ghadermazi, Mohammad
, p. 15052 - 15064 (2020/05/05)
A composite of Ni nanoparticles incorporated in Kryptofix 22 conjugated magnetic nano-graphene oxide, CoFe2O4@GO-K 22·Ni, was synthesized via the grafting of Kryptofix 22 moieties on the magnetic nano-graphene oxide surface, followed by reaction of the nanocomposite with nickel nitrate. The Kryptofix 22 host material unit cavities can stabilize the Ni nanoparticles effectively and prevent their aggregation and separation from the surface. Characterization of the catalysts by FT-IR, FE-SEM, TGA, ICP, EDX, XRD, VSM and BET aided understanding the catalyst structure and morphology. This catalyst was efficiently applied for the synthesis of 1,4-benzodiazepine derivatives. The main advantages of the method are mild reaction conditions, inexpensive catalyst, it is environmentally benign, has high to excellent yields and shorter reaction times. This organometallic catalyst can be easily separated from a reaction mixture and was successfully examined for six runs with a slight loss of catalytic activity.
Synthesis and characterization of CoFe2O4@SiO2@NH-NH2-PCuW as an acidic nano catalyst for the synthesis of 1,4-benzodiazepines and a powerful dye remover
Savari, Ali,Heidarizadeh, Fariba,Pourreza, Nahid
, p. 233 - 247 (2019/05/08)
A novel magnetic heterogeneous nanocatalyst CoFe2O4@SiO2@NH-NH2-PCuW was synthesized and characterized. This powerful catalyst possesses Br?nsted and Lewis acid properties. The presence of Cu enhances the acidity of this catalyst because of the increase in the electron deficiency of polyoxometalate. It was successfully applied for the easy and efficient one-pot synthesis of 1,4-benzodiazepine derivatives directly from dimedone, o-phenylenediamine, and an aromatic aldehyde under a solvent-free condition at 80 °C. High yields in short reaction times, easy work-up, and environmental friendliness are some of the advantages of this protocol. Also, this nanocatalyst could conveniently be recovered by a magnetic field and reused several times without a significant loss of catalytic efficiency. The synthesized nanocatalyst CoFe2O4@SiO2@NH-NH2-PCuW also proved to be an excellent adsorbent for dye removal. These properties are related to the high surface area because of the nanostructure and high acidity due to the presence of Cu in polyoxometalate. Moreover, magnetic properties help better recovering of this adsorbent for dye removed from wastewater.
