82431-18-3Relevant articles and documents
Practical Multigram Syntheses of Benzocyclobutenediones
South, Michael S.,Liebeskind, Lanny S.
, p. 3815 - 3821 (2007/10/02)
Experimentally simple syntheses of benzocyclobutenedione and substituted benzocyclobutenediones (3-OH; 4-OH; 4-Me; 3-OH, 5-Me) are described which allow the synthesis of these compounds on large scale from inexpensive starting materials.The regiospecific and stereoselective cycloaddition of trimethylsiloxy dienes to 1,4-dichloro-3,3,4-trifluorocyclobutene forms the basis of the synthesis of the substituted benzocyclobutenediones.