82444-82-4

Basic information

• Product Name: 4-(1,2,4-triazol-1-yl)-1-<5'-O-(dimethoxytrityl)-3'-O-((p-chlorophenoxy)(2-cyanoethoxy)phosphoryl)-2'-O-(tert-butyldimetylsilyl)-β-D-ribofuranosyl>pyrimidin-2-(1H)-one
• CAS NO: 82444-82-4
• Molecular Weight: 955.476
• Mol File: 82444-82-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1,2,4-triazol-1-yl)-1-<5'-O-(dimethoxytrityl)-3'-O-((p-chlorophenoxy)(2-cyanoethoxy)phosphoryl)-2'-O-(tert-butyldimetylsilyl)-β-D-ribofuranosyl>pyrimidin-2-(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,2,4-triazol-1-yl)-1-<5'-O-(dimethoxytrityl)-3'-O-((p-chlorophenoxy)(2-cyanoethoxy)phosphoryl)-2'-O-(tert-butyldimetylsilyl)-β-D-ribofuranosyl>pyrimidin-2-(1H)-one(82444-82-4)
• EPA Substance Registry System: 4-(1,2,4-triazol-1-yl)-1-<5'-O-(dimethoxytrityl)-3'-O-((p-chlorophenoxy)(2-cyanoethoxy)phosphoryl)-2'-O-(tert-butyldimetylsilyl)-β-D-ribofuranosyl>pyrimidin-2-(1H)-one(82444-82-4)

Safety Data

• Hazardous Substances Data: 82444-82-4(Hazardous Substances Data)

Upstream product

• 81246-80-2 5'-O-dimethoxytrityl-2'-O-tert-butyldimethylsilyl uridine 
• 288-88-0 1,2,4-Triazole 
• 81265-94-3 5'-dimethoxytrityl 2'-tert-butyldimethyl silyl uridine 3'-p-chlorophenyl β-cyanoethyl phosphotriester 
• 772-79-2 4-chlorophenylphosphorodichloridate 
• 109-78-4 3-Hydroxypropionitrile 

Downstream Products

• 82444-92-6 Phosphoric acid (2R,3R,4R,5R)-4-(tert-butyl-dimethyl-silanyloxy)-2-hydroxymethyl-5-(2-oxo-4-[1,2,4]triazol-1-yl-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 2-cyano-ethyl ester 

Relevant articles and documents

Synthesis of 4-(1,2,4-Triazol-1-yl)pyrimidin-2(1H)-one Ribonucleotide and Its Application in Synthesis of Oligoribonucleotides

5'-O-(Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)uridine (21) was converted to 4-(1,2,4-triazol-1-yl)-1-pyrimidin-2(1H)-one (20)