82481-34-3

Basic information

• Product Name: 7-methoxy-3-(4-methoxybenzyl)-6-(4-methoxyphenyl)imidazo[1,2-b][1,2,4,5]tetrazine
• Synonyms: Imidazo(1,2-b)-1,2,4,5-tetrazine, 7-methoxy-6-(4-methoxyphenyl)-3-((4-methoxyphenyl)methyl)-; Imidazo[1,2-b]-1,2,4,5-tetrazine, 7-methoxy-6-(4-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-
• CAS NO: 82481-34-3
• Molecular Formula: C₂₀H₁₉N₅O₃
• Molecular Weight: 377.3966
• Mol File: 82481-34-3.mol
• Article Data: 1

Chemical Properties

• Density: 1.31g/cm³
• Refractive Index: 1.647
• CAS DataBase Reference: 7-methoxy-3-(4-methoxybenzyl)-6-(4-methoxyphenyl)imidazo[1,2-b][1,2,4,5]tetrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-3-(4-methoxybenzyl)-6-(4-methoxyphenyl)imidazo[1,2-b][1,2,4,5]tetrazine(82481-34-3)
• EPA Substance Registry System: 7-methoxy-3-(4-methoxybenzyl)-6-(4-methoxyphenyl)imidazo[1,2-b][1,2,4,5]tetrazine(82481-34-3)

Safety Data

• Hazardous Substances Data: 82481-34-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 14141-65-2 3,6-dibenzyl-1,2,4,5-tetrazine 
• 82481-29-6 3,6-bis(4-methoxybenzyl)-s-tetrazine 

Relevant articles and documents

Investigations into the Mechanism of the Action of Alkali in Methanol on 3,6-Dibenzyl-s-tetrazines and their 1,4-Dihydro-derivatives: the Role of s-Tetrazines as Hydride Acceptors and an X-Ray Determination of the Structure of 3,6-Bis(4-chlorobenzyl)-1,4-dihydro-s-tetrazine

Evidence is presented for the mechanism of the reaction of potassium hydroxide with 3,6-dibenzyl-s-tetrazines in which some tetrazine molecules act as hydride acceptors to become dihydro-derivatives which, in turn, react with alkali in a competing reaction to form the corresponding 1,3,4-oxadiazoles.The known action of alkali on 3,6-dibenzyl-1,4-dihydro-s-tetrazines to form 1,3,4-oxadiazoles has been shown to require the presence of an oxidising agent and tetrazine can play this role.The structures of the dihydro-derivatives of s-tetrazines have been in doubt, being called 1,2- and/or 1,4-compounds almost at random, but an X-ray determination of the structure of the dihydro-derivative of 3,6-bis(4-chlorobenzyl)-s-tetrazine has shown conclusively that it exists as 1,4-dihydro-compound.