824943-43-3

Basic information

• Product Name: (S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester
• Synonyms: (S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester
• CAS NO: 824943-43-3
• Molecular Weight: 337.373
• Mol File: 824943-43-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester(824943-43-3)
• EPA Substance Registry System: (S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester(824943-43-3)

Safety Data

• Hazardous Substances Data: 824943-43-3(Hazardous Substances Data)

Upstream product

• 852822-01-6 (S)-2-Benzyloxycarbonylamino-5-[1,3]dioxolan-2-yl-pentanoic acid 
• 74-88-4 methyl iodide 
• 215054-80-1 (S)-2-amino-5-(1,3-dioxolane-2-yl)-pentanoic acid 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 

Downstream Products

• 189952-46-3 (2S,5R)-methyl 5-hydroxypiperidine-2-carboxylate 
• 824943-40-0 (2S,5R)-5-hydroxy-piperidine-2-carboxylic acid hydrochloride 
• 824943-60-4 (3S,4aR,10aR)-5,7-Dimethoxy-1,2,3,4a,9,10a-hexahydro-10-oxa-4-aza-phenanthrene-3,4-dicarboxylic acid 4-benzyl ester 3-methyl ester 
• 824943-58-0 (2S,5R)-5-(3,5-dimethoxy-benzyloxy)-6-methoxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 852822-08-3 (2S,5R,6S)-5-Acetoxy-6-(2-oxo-2-phenyl-ethyl)-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 824943-47-7 (2S,5R)-5-acetoxy-6-methoxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 824943-45-5 (2S,5R)-5-hydroxy-6-methoxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 227758-97-6 (2S)-3,4-dihydro-2H-pyridine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 875574-94-0 (S)-benzyl 3-(2-(5-(1,3-dioxolan-2-yl)-1-methoxy-1-oxopentan-2-ylamino)-2-oxoethyl)-1H-indole-1-carboxylate 
• 875574-86-0 (S)-methyl 2-((S)-3-(benzyloxycarbonylamino)-3-phenylpropanamido)-5-(1,3-dioxolan-2-yl)pentanoate 
• 875574-87-1 (S)-methyl 2-((R)-3-(benzyloxycarbonylamino)-3-phenylpropanamido)-5-(1,3-dioxolan-2-yl)pentanoate 
• 875574-64-4 (S)-methyl 2-((S)-2-(benzyloxycarbonylamino)-3-phenylpropanamido)-5-(1,3-dioxolan-2-yl)pentanoate 
• 875574-65-5 (S)-methyl 2-((R)-2-(benzyloxycarbonylamino)-3-phenylpropanamido)-5-(1,3-dioxolan-2-yl)pentanoate 
• 875574-96-2 (S)-methyl 2-((R)-2-(benzyloxycarbonylamino)hex-5-enamido)-5-(1,3-dioxolan-2-yl)pentanoate 

Relevant articles and documents

Diastereoselective synthesis of (2Ss,5R)-5-hydroxypipecolic acid and 6-substituted derivatives

(Chemical Equation Presented) Herein, we report a diastereoselective synthesis of the natural product (2S,5R)-5-hydroxypipecolic acid and 6-substituted derivatives thereof. The key step in the synthetic sequence is a novel highly diastereoselective epoxidation reaction of an enantiomerically pure cyclic enamide intermediate.