825-59-2 Usage
General Description
2,5-DIMETHYL-PYRIDINEFORMAMIDE is a chemical compound with the molecular formula C7H10N2O. It is a formamide derivative of pyridine, with two methyl groups attached to the 2 and 5 positions of the pyridine ring. 2,5-DIMETHYL-PYRIDINEFORMAMIDE is commonly used as a building block or starting material for the synthesis of various pharmaceuticals and agrochemicals. It can also be utilized as a solvent in chemical reactions and as a reagent in organic synthesis. 2,5-DIMETHYL-PYRIDINEFORMAMIDE has a variety of industrial applications and is typically handled and stored in regulated conditions due to its potential health and safety hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 825-59-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,2 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 825-59:
(5*8)+(4*2)+(3*5)+(2*5)+(1*9)=82
82 % 10 = 2
So 825-59-2 is a valid CAS Registry Number.
825-59-2Relevant articles and documents
Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl] acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Van Zandt, Michael C.,Doan, Brian,Sawicki, Diane R.,Sredy, Janet,Podjarny, Alberto D.
supporting information; experimental part, p. 2006 - 2008 (2009/11/30)
Efforts to identify treatments for chronic diabetic complications have resulted in the discovery of a novel series of highly potent and selective [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl] acetic acid aldose reductase inhibitors. The lead candidate, [6-methyl-3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyri din-1-yl]acetic acid example 16, inhibits aldose reductase with an IC50 of 8 nM, while being inactive against aldehyde reductase (IC50 > 100 μM), a related enzyme involved in the detoxification of reactive aldehydes.
