82516-17-4

Basic information

• Product Name: 1-Piperazineaceticacid,methylester(9CI)
• Synonyms: PIPERAZIN-1-YLMETHYL ACETATE;1-piperazineacetic acid, methyl ester;methyl piperazin-1-ylacetate dihydrochloride;methyl 1-piperazinylacetate(SALTDATA: 2HCl);Methyl 1-piperazinylacetate dihydrochloride;2-(1-piperazinyl)acetic acid methyl ester;2-piperazin-1-ylacetic acid methyl ester;methyl 2-piperazin-1-ylethanoate
• CAS NO: 82516-17-4
• Molecular Formula: C₇H₁₄N₂O₂
• Molecular Weight: 158.2
• Product Categories: PIPERIDINE
• Mol File: 82516-17-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-Piperazineaceticacid,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazineaceticacid,methylester(9CI)(82516-17-4)
• EPA Substance Registry System: 1-Piperazineaceticacid,methylester(9CI)(82516-17-4)

Safety Data

• Statements: 36
• Safety Statements: 26
• HazardClass: IRRITANT
• Hazardous Substances Data: 82516-17-4(Hazardous Substances Data)

Usage

Physical state

Crystalline solid at room temperature

Common uses

+ Pharmaceutical industry (precursor in the synthesis of various medications)
+ Research and development laboratories (building block for creating new chemical compounds)

Potential properties

+ Anticonvulsant
+ Antinociceptive

Possible applications in drug development

+ Treatment of neurological disorders
+ Pain management

Upstream product

• 731810-20-1 tert-butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate 
• 110-85-0 piperazine 
• 96-32-2 bromoacetic acid methyl ester 
• 96-34-4 methyl chloroacetate 

Downstream Products

• 198627-26-8 trans-4-[(1-tert-Butyloxycarbonylpiperidin-4-yl)methyloxy]-1-(4-methoxycarbonylmethylpiperazino)cyclohexane 

Relevant articles and documents

Synthesis and Herbicidal and Antioxidant Activity of a Series of Hetero- and Carbocyclic Derivatives of Monochloroacetic Acid

Abstract: Monochloroacetic acid esters and amides containing carbo- and heterocycles and heterocyclic esters and amides derived from commercial aryloxyacetyl chlorides were synthesized. The structures of the compounds were confirmed by 1Н and 13С spectroscopy. The herbicidal activity of the substances was studied with respect to mono- and dicotyledonous plants. The relative antioxidant activity of the compounds was studied by recording the luminol-dependent chemiluminescence. The experimental data, on the whole, confirm that the development of herbicides containing acetal and gem-dichlorocyclopropane fragments is appropriate and promising.

5-HTX MODULATORS

This invention relates to compounds which bind to serotonin receptors inside or outside the central nervous system, in particular compounds which bind to the 5-HT2 or 5-HT7 receptors, their preparation and use, compositions containing them, and methods of treatment using them.