82543-85-9Relevant articles and documents
A kind of amino acid- the amine decorates composition and its preparation method and application
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Paragraph 0058; 0059; 0066, (2017/04/05)
The invention belongs to the field of medicinal chemistry and in particular relates to amino acid-amine conjugate and a preparation method and application thereof. A general formula of the amino acid-amine conjugate is shown in the specification. According to the amino acid-amine conjugate, amino acid and amine are combined together, the water solubility, biological properties and drug targeting of amine compounds can be improved, and anti-cancer targeting can be realized.
Determination of covalently bound hypusine and deoxyhypusine to protein using submilligram of protein samples by HPLC
Beppu, Takanobu,Shirahata, Akira,Samejima, Keijiro
, p. 1 - 5 (2007/10/03)
A sensitive and reliable method for the determination of hypusine and deoxyhypusine in elF-5A protein, an initiation factor of protein synthesis, was developed. An advantage of this method is the use of N(ε)-(5- aminopentyl)lysine, an analogue of deoxyhyp