82576-63-4 Usage
General Description
N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is a chemical compound that belongs to the class of organic compounds known as alkyl phosphorochloridothioates. It is a powerful bifunctional alkylating agent, commonly used in chemotherapy and cancer treatment. N,N-bis(2-chloroethyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,2-oxazaphosphinan-2-amine 2-oxide is known for its ability to crosslink DNA, causing damage to the genetic material of cancer cells and ultimately leading to cell death. However, it also poses a high risk of toxicity and adverse side effects, making it a highly regulated and controlled substance. Due to its detrimental effects, it is crucial to handle and administer this compound with extreme caution and under strict medical supervision.
Check Digit Verification of cas no
The CAS Registry Mumber 82576-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,7 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 82576-63:
(7*8)+(6*2)+(5*5)+(4*7)+(3*6)+(2*6)+(1*3)=154
154 % 10 = 4
So 82576-63-4 is a valid CAS Registry Number.
82576-63-4Relevant articles and documents
Synthesis and study of a spin-labeled cyclophosphamide analogue, 3-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide
Tsui,Robey,Engle,Ludeman,Zon
, p. 1106 - 1110 (1982)
3-(1-Oxy-2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide (7) was isolated in 36% yield following H2O2-Na2WO4 oxidation of 3-(2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide (6), which was synthesized in th