82577-50-2

Basic information

• Product Name: 3,4-Furandicarboxylic acid, 2-(4-methylphenyl)-, dimethyl ester
• CAS NO: 82577-50-2
• Molecular Formula: C15H14O5
• Molecular Weight: 274.273
• Mol File: 82577-50-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3,4-Furandicarboxylic acid, 2-(4-methylphenyl)-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Furandicarboxylic acid, 2-(4-methylphenyl)-, dimethyl ester(82577-50-2)
• EPA Substance Registry System: 3,4-Furandicarboxylic acid, 2-(4-methylphenyl)-, dimethyl ester(82577-50-2)

Safety Data

• Hazardous Substances Data: 82577-50-2(Hazardous Substances Data)

Upstream product

• 762-42-5 dimethyl acetylenedicarboxylate 
• 69836-59-5 1-p-Tolyl-7-oxa-bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester 
• 476000-52-9 3-p-tolyl-2,4-dioxa-cyclopenta[b]naphthalen-9-one 
• 203629-49-6 3-[1,3]Dioxan-2-yl-2-(hydroxy-p-tolyl-methyl)-chromen-4-one 
• 104-87-0 4-methyl-benzaldehyde 
• 4209-24-9 p-methylphenacyl chloride 
• 619-41-0 4-(bromoacetyl)toluene 
• 476000-77-8 C₂₄H₁₈O₇ 
• 82577-47-7 dimethyl 3-(p-tolyl)-3,6-endoxotetrahydro-4,5-phthalate 

Downstream Products

• 82577-55-7 2-(p-tolyl)-3,4-bis(carbomethoxy)-5-nitrofuran 
• 82577-52-4 dimethyl 2-bromo-5-p-tolylfuran-3,4-dicarboxylate 
• 87645-54-3 2-(p-Tolyl)-3,4-bis(carboxy)furan 
• 87645-59-8 2-(p-Tolyl)-3,6-dioxofuro<3,4-d>pyridazine 
• 87645-52-1 2-(p-Tolyl)-3,4-bis(chlorocarbonyl)furan 
• 87645-56-5 2-(p-Tolyl)furan-3,4-dicarboxylic acid diamide 

Relevant articles and documents

Regiospecific synthesis of polysubstituted furans with mono- to tricarboxylates from various sulfonium acylmethylides and acetylenic esters

Polysubstituted furans were prepared in moderate to good yields from various sulfur ylides and alkyl acetylenic carboxylates. The direct reactions of dimethylsulfonium acylmethylides with dialkyl acetylenedicarboxylates afforded dialkyl furan-3,4-dicarboxylates through a tandem sequence of Michael addition, intramolecular nucleophilic addition, 4π ring opening, intramolecular Michael addition, and elimination. The method was extended to synthesize furan-3-carboxylate, -2,4-dicarboxylates, and -2,3,4-tricarboxylates as well. The current method provides a direct and simple strategy in the synthesis of structurally diverse polysubstituted furans with mono to tricarboxylate groups from safe and readily available dimethylsulfonium acylmethylides and different alkyl acetylenic carboxylates.

DABCO-catalyzed reaction of α-halo carbonyl compounds with dimethyl acetylenedicarboxylate: A novel method for the preparation of polysubstituted furans and highly functionalized 2H-pyrans

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SYNTHESIS AND ELECTROPHILIC SUBSTITUTION REACTIONS OF 2-ARYL-3,4-BIS(CARBOMETHOXY)FURANS

The thermal decomposition of the products of hydrogenation of the adducts obtained from arylfurans and dimethyl acetylenedicarboxylate leads to the formation of 2-aryl-3,4-bis(carbomethoxy)furans.The bromination of these compounds takes place in the 5 pos