82585-42-0 Usage
Description
(1Z)-2-amino-1-[4-(trifluoromethyl)phenyl]ethanone oxime is an oxime of 2-amino-1-(4-(trifluoromethyl)phenyl)ethanone, a ketone that contains a trifluoromethyl group and a phenyl group. This chemical compound is utilized in organic synthesis and pharmaceutical research as a building block for the creation of various compounds. Its unique structure and properties render it a valuable intermediate in the production of pharmaceuticals and agrochemicals. The presence of the oxime group in its structure adds versatility to its use in chemical reactions, making it a promising candidate for medicinal chemistry, where it can be employed in the synthesis of novel compounds with diverse biological activities.
Uses
Used in Organic Synthesis:
(1Z)-2-amino-1-[4-(trifluoromethyl)phenyl]ethanone oxime is used as a building block in organic synthesis for the creation of a variety of compounds. Its unique structure allows it to be a versatile component in the synthesis process, contributing to the development of new chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1Z)-2-amino-1-[4-(trifluoromethyl)phenyl]ethanone oxime is used as an intermediate in the production of pharmaceuticals. Its properties make it a valuable component in the synthesis of drugs, potentially leading to the development of new medications with improved efficacy and safety profiles.
Used in Agrochemical Production:
(1Z)-2-amino-1-[4-(trifluoromethyl)phenyl]ethanone oxime also finds application in the agrochemical sector, where it serves as an intermediate in the synthesis of various agrochemicals. Its role in this industry is crucial for the development of new pesticides, herbicides, and other agricultural chemicals that can enhance crop protection and yield.
Used in Medicinal Chemistry:
In medicinal chemistry, (1Z)-2-amino-1-[4-(trifluoromethyl)phenyl]ethanone oxime is used for the synthesis of novel compounds with diverse biological activities. Its oxime form provides additional reactivity and functional group manipulation options, which can be leveraged to design and create new pharmaceutical agents with potential therapeutic benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 82585-42-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,8 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 82585-42:
(7*8)+(6*2)+(5*5)+(4*8)+(3*5)+(2*4)+(1*2)=150
150 % 10 = 0
So 82585-42-0 is a valid CAS Registry Number.
82585-42-0Relevant articles and documents
New Anticancer Agents: Synthesis of 1,2-Dihydropyridopyrizines (1-Deaza-7,8-dihydropteridines)
Temple, Carroll,Wheeler, Glynn P.,Elliott, Robert D.,Rose, Jerry D.,Kussner, Conrad L.,et al.
, p. 1045 - 1050 (2007/10/02)
Reaction of α-aminoacetophenone oximes (2) with ethyl 6-amino-4-chloro-5-nitropyridine-2-carbamate (1) gave ethyl 6-amino-5-nitro-4-pyridine-2-carbamate oximes (3), which were hydrolyzed under acidic conditions to give the corresponding ketones (4).Related pyridines substituted with keto side chain were prepared from 1 and 1,3-diaminopropanone oximes and by oxidation of the side-chain hydroxy group of ethyl 6-amino-4-amino>-5-nitropyridine-7-carbamates (6).Catalytic hydrogenation of the nitro group of 4 over Raney nickel in a large volume of ethanol gave the 1-deaza-7,8-dihydropteridines (7).Several of the oximes 3 were successfully hydrogenated to give 7 directly.The resulting 1-deaza-7,8-dihydropteridines showed potent cytotoxicity against cultured L1210 cells and significant anticancer activity against lymphocytic leukemia P-388 in mice.THese biological activities are attributed to the accumulation of cells at mitosis.
