82586-71-8

Basic information

• Product Name: 2-DIMETHYL AMINO METHYL-4-CHLORO METHYL THIAZOLE HCL
• Synonyms: 2-DIMETHYL AMINO METHYL-4-CHLORO METHYL THIAZOLE HCL;2-DIMETHYL AMINO METHYL-4-CHLORO METHYL THIAZOLE HYDROCHLORIDE;4-(chloromethyl)-N,N-dimethyl-2-Thiazolemethanamine hydrochloride;N-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}-N,N-dimethylamine hydrochloride
• CAS NO: 82586-71-8
• Molecular Formula: C₇H₁₁ClN₂S*ClH
• Molecular Weight: 227.15
• Mol File: 82586-71-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-DIMETHYL AMINO METHYL-4-CHLORO METHYL THIAZOLE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-DIMETHYL AMINO METHYL-4-CHLORO METHYL THIAZOLE HCL(82586-71-8)
• EPA Substance Registry System: 2-DIMETHYL AMINO METHYL-4-CHLORO METHYL THIAZOLE HCL(82586-71-8)

Safety Data

• Hazardous Substances Data: 82586-71-8(Hazardous Substances Data)

Upstream product

• 92759-37-0 4-Hydroxy-4-(chloromethyl)-2-<(dimethylamino)methyl>thiazoline 
• 10026-13-8 phosphorus pentachloride 
• 107-06-2 1,2-dichloro-ethane 
• 27366-72-9 2-dimethylaminothioacetamide hydrochloride 
• 534-07-6 1,3-Dichloroacetone 
• 27507-28-4 ((dimethylamino)methyl)thioformamide 
• 82586-70-7 4-Hydroxymethyl-2-dimethylaminomethyl-thiazol-hydrochlorid 

Downstream Products

• 78441-62-0 4-[[(2-aminoethyl)thio]-methyl]-N,N-dimethyl-2-thiazolemethanamine 

Relevant articles and documents

Spectroscopic Evidence for a Spirooxirane Intermediate in the Synthesis of 4-(Hydroxymethyl)-2-thiazole

The synthesis of 4-(hydroxymethyl)thiazole derivatives from the corresponding 4-(chloromethyl)-4-hydroxythiazole derivatives have been speculated to proceed through spirooxirane intermediates.NMR spectroscopy was used to provide evidence for the existence of such an intermediate in the synthesis of 4-(hydroxymethyl)-2-thiazole.Experimental conditions for the optimum formation and stabilization of a suspect intermediate were determined and spectral data obtained to support the speculated structure.Comparison were made between couplings constants predicted in molecular models and the experimental data.

2-[2-(2-AMINOALKYL-4-THIAZOLYLMETHYLTHIO)ALKYL]-AMINO-5-SUBSTITUTED-4-PYRIMIDONES

2-2-(2-aminoalkyl-4-thiazolylmethylthio)-alkylene!amino-5-aromatic-substitute d alkylene-4-pyrimidones and related compounds, H. sub.2 receptor antagonists, useful in inhibiting gastric acid secretion in mammals.