82597-81-7 Usage
Description
(10beta)-6,8-dimethyl-8,9-didehydroergoline, also known as lysergic acid, is a semi-synthetic compound derived from ergotamine, a naturally occurring alkaloid found in the ergot fungus. It is primarily known for its psychoactive effects and is the primary component of the hallucinogenic drug LSD. (10beta)-6,8-dimethyl-8,9-didehydroergoline acts on the serotonin receptors in the brain, leading to its hallucinogenic and psychoactive effects. Additionally, it has been studied for its potential therapeutic applications in treating mental health disorders and addiction.
Uses
Used in Pharmaceutical Industry:
(10beta)-6,8-dimethyl-8,9-didehydroergoline is used as an active pharmaceutical ingredient for the development of medications targeting mental health disorders and addiction. Its interaction with serotonin receptors in the brain offers potential therapeutic benefits for conditions such as depression, anxiety, and substance abuse.
Used in Research Applications:
In the field of neuroscience and psychopharmacology, (10beta)-6,8-dimethyl-8,9-didehydroergoline serves as a research tool to study the effects of serotonin receptor modulation on brain function and behavior. This helps scientists better understand the mechanisms underlying mental health disorders and develop more effective treatments.
Used in Drug Development:
(10beta)-6,8-dimethyl-8,9-didehydroergoline is utilized in the development of new drugs with improved safety and efficacy profiles. By understanding its mechanism of action and potential therapeutic benefits, researchers can design and synthesize novel compounds with similar or enhanced properties for the treatment of various mental health conditions and addictions.
Check Digit Verification of cas no
The CAS Registry Mumber 82597-81-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,5,9 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 82597-81:
(7*8)+(6*2)+(5*5)+(4*9)+(3*7)+(2*8)+(1*1)=167
167 % 10 = 7
So 82597-81-7 is a valid CAS Registry Number.
82597-81-7Relevant articles and documents
Simple total syntheses of (-)-ergot alkaloids and their (+)-enantiomers by a common synthesis method utilizing optical resolution
Somei, Masanori,Nakagawa, Kyoko
, p. 1263 - 1266 (2007/10/03)
The first and simple total syntheses of (-)-isochanoclavine-1 ((-)-1b), (-)-agroclavine ((-)-3), (-)-agroclavine-1 ((-)-4), and (-)-norchanoclavine-1 ((-)-5c) and their (+)-enantiomers are achieved from indole-3-carboxaldehyde (8) by a common synthesis method utilizing optical resolution. Absolute configuration of (-)-agroclavine-1 is determined to be 5R and 10S for the first time. Preparations of both enantiomers of chanoclavine-1 (1c) are also included.
SHORT-STEP SYNTHESIS OF THE ERGOT ALKALOIDS, (+/-)-NORCHANOCLAVINE-I, (+/-)-CHANOCLAVINE-I, (+/-)-ISOCHANOCLAVINE-I, and (+/-)-AGROCLAVINE
Somei, Masanori,Makita, Yoshihiko,Yamada, Fumio
, p. 948 - 950 (2007/10/02)
The simple total synthesis of the ergot alkaloids, (+/-)-norchanoclavine-I, (+/-)-chanoclavine-I, (+/-)-isochanoclavine-I, and (+/-)-agroclavine was achieved by a practical and common synthesis method.A new regio-selective oxidation of the Z-methyl group of the isoprenyl system with selenium dioxide is described.Keywords - (+/-)-norchanoclavine-I; (+/-)-norisochanoclavine-I; (+/-)-chanoclavine-I; (+/-)-isochanoclavine-I; (+/-)-agroclavine; ergot alkaloid; total synthesis; common synthesis method; new oxidation
Dehydrogenation with phenylseleninic anhydride in the total synthesis of ergot alkaloids
Ninomiya,Hashimoto,Kiguchi,et al.
, p. 4187 - 4190 (2007/10/02)
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