826-10-8

Basic information

• Product Name: (R)-N,alpha-dimethylphenethylamine hydrochloride
• Synonyms: (R)-N,alpha-dimethylphenethylamine hydrochloride;Benzeneethanamine, N,a-dimethyl-, hydrochloride, (aR)- (9CI);Benzeneethanamine, N,a-dimethyl-, hydrochloride, (R)-;l-Methamphetamine hydrochloride;Einecs 212-552-1;L-Desoxyephedrine hydrochloride;L-Methamphetamine HCl;L-N-Methyl-beta-phenylisopropylamine hydrochloride
• CAS NO: 826-10-8
• Molecular Formula: C₁₀H₁₅N*ClH
• Molecular Weight: 185.69374
• EINECS: 212-552-1
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 826-10-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 172-174°C
• Appearance: /
• Storage Temp.: Controlled Substance, -20°C Freezer
• CAS DataBase Reference: (R)-N,alpha-dimethylphenethylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N,alpha-dimethylphenethylamine hydrochloride(826-10-8)
• EPA Substance Registry System: (R)-N,alpha-dimethylphenethylamine hydrochloride(826-10-8)

Safety Data

• Hazard Codes: T
• Statements: 63-23/24/25
• Safety Statements: 22-36/37/39-45
• Hazardous Substances Data: 826-10-8(Hazardous Substances Data)

Usage

Description

(?)-Methamphetamine (hydrochloride) (Item No. 13998) is an analytical reference material categorized as an amphetamine. It is the less physiologically active isomer of (±)-methamphetamine ( | 14216). (?)-Methamphetamine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

Chemical Properties

Off-White to Pale Yellow Solid

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. A powerful central nervous system stimulant. Catltion: Excessive use may lead to tolerance and habituation. When heated to decomposition it emits veq7 toxic fumes of HCl and NOx. See also BENZEDRINE.

Upstream product

• 14611-52-0 (R)-(-)-deprenyl hydrochloride 

Downstream Products

• 1247027-65-1 (R)-N-Methyl-N-(1-phenylpropan-2-yl)-1H-imidazole-1-carboxamide 
• 2323-36-6 SELEGILINE 

Relevant articles and documents

Trace decomposition of selegiline. Use of worst-case kinetics for a stable drug

A solution of selegiline hydrochloride reference standard, which contained no detectable impurities at the time of its preparation, was found by HPLC to contain a trace of a compound at the locus of methamphetamine when analyzed after 1 year. Heating selegiline solutions at pH 7 and 105 °C produced methamphetamine as the major product at a rate which closely followed the first-order rate equation. Using only these data and worst-case assumptions, rate constants were estimated at various temperatures; the activation energy was estimated to be about 25 kcal, and the stability-indicating validity of the assay used was reaffirmed. Selegiline undergoes degradation at a negligibly slow rate.