827-03-2

Basic information

• Product Name: 1,3-Cyclopentanedione, 2-isopentyl-
• Synonyms: 1,3-Cyclopentanedione, 2-isopentyl-;2-Isopentyl-1,3-cyclopentanedione
• CAS NO: 827-03-2
• Molecular Formula: C10H16 O2
• Molecular Weight: 0
• Mol File: 827-03-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Cyclopentanedione, 2-isopentyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclopentanedione, 2-isopentyl-(827-03-2)
• EPA Substance Registry System: 1,3-Cyclopentanedione, 2-isopentyl-(827-03-2)

Safety Data

• Hazardous Substances Data: 827-03-2(Hazardous Substances Data)

Usage

General Description

1,3-Cyclopentanedione, 2-isopentyl- is a chemical compound that is also known as 2-Isopentyl-1,3-cyclopentanedione or dehydrocineole. It is a fragrance ingredient that is commonly used in the manufacturing of perfumes, soaps, and other beauty products. It has a sweet, floral scent and is often used to add a fruity or citrus note to fragrances. The compound is also used in food flavorings and as a flavoring agent in the culinary industry. However, it is important to note that 1,3-Cyclopentanedione, 2-isopentyl- may cause skin irritation and should be used with caution.

Upstream product

• 3859-41-4 1,3-cyclopentadione 
• 590-86-3 isovaleraldehyde 

Relevant articles and documents

Direct amino acid-catalyzed cascade biomimetic reductive alkylations: Application to the asymmetric synthesis of Hajos-Parrish ketone analogues

A direct amino acid-catalyzed chemo- and enantioselective process for the double cascade synthesis of highly substituted 2-alkyl-cyclopentane-1,3-diones, 2-alkyl-3-methoxy-cyclopent-2-enones and Hajos-Parrish (H-P) ketone analogs is presented via reductive alkylation chemistry. For the first time, we have developed a single-step alkylation of cyclopentane-1,3-dione with aldehydes/ketones and a Hantzsch ester through an organocatalytic reductive alkylation strategy. A direct combination of amino acid-catalyzed cascade olefination-hydrogenation and cascade Robinson annulations of cyclopentane-1,3-dione, aldehydes/ketones, a Hantzsch ester and methyl vinyl ketone furnished the highly functionalized H-P ketone analogues in good to high yields and with excellent enantioselectivities. Many of the reductive alkylation products have shown direct applications in pharmaceutical chemistry.