82721-80-0

Basic information

• Product Name: Benzene, 1-methyl-4-[(phenylsulfonyl)ethynyl]-
• CAS NO: 82721-80-0
• Molecular Formula: C15H12O2S
• Molecular Weight: 256.325
• Mol File: 82721-80-0.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-4-[(phenylsulfonyl)ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-4-[(phenylsulfonyl)ethynyl]-(82721-80-0)
• EPA Substance Registry System: Benzene, 1-methyl-4-[(phenylsulfonyl)ethynyl]-(82721-80-0)

Safety Data

• Hazardous Substances Data: 82721-80-0(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 103725-11-7 α-chloro-α-diethoxyphosphorylmethyl phenyl sulfone 
• 82721-76-4 1-((E)-2-Benzenesulfonyl-1-phenylselanyl-vinyl)-4-methyl-benzene 
• 206132-41-4 5-benzenesulfonyl-4-p-tolyl-[1,2,3]selenadiazole 
• 766-97-2 4-n-methylphenylacetylene 
• 873-55-2 sodium benzenesulfonate 
• 383126-33-8 1-((Z)-2-Benzenesulfonyl-1-iodo-vinyl)-4-methyl-benzene 
• 38488-14-1 2-(phenylsulfonyl)-1-(p-tolyl)ethanone 
• 60805-71-2 phenylselenyl benzenesulfonate 
• 2227-58-9 3-(4-methylphenyl)prop-2-ynoic acid 
• 619-41-0 4-(bromoacetyl)toluene 
• 91075-94-4 1-p-methylphenylethynyl phenyl sulfide 
• 882-33-7 diphenyldisulfane 
• 33675-56-8 1-(iodoethynyl)-4-methylbenzene 

Downstream Products

• 1217128-05-6 2-(2-(phenylsulfonyl)-1-(1H-pyrrol-2-yl)-1-p-tolylethyl)-1H-pyrrole 
• 92078-70-1 1-(cyclopentylidenemethyl)-4-methylbenzene 
• 61692-91-9 1-methyl-4-[3-(4-methylphenyl)prop-2-yn-1-yl]benzene 
• 38488-14-1 2-(phenylsulfonyl)-1-(p-tolyl)ethanone 
• 30166-88-2 (E)-2-(4-methylphenyl)ethenyl phenyl sulfone 
• 583872-48-4 Z-2-(4'-tolyl)-1-(phenylsulfonyl)ethene 

Relevant articles and documents

Boryl Radical-Mediated C?H Activation of Inactivated Alkanes for the Synthesis of Internal Alkynes

An intriguing pyridine-boryl radical-mediated C?H alkynylation reaction of inactivated alkanes was described. The reaction features mild operation condition and wide substrate scope, and affords the corresponding products in moderate to good yields. Notab

Radical-mediated sulfonyl alkynylation, allylation, and cyanation of propellane

Bicyclo[1.1.1]pentane (BCP) is widely applied as the bioisostere for aryl, internal alkynes, andtert-butyl groups in medicinal chemistry. We herein disclose an efficient and practical preparation of sulfonyl alkynyl/allyl/cyano-substituted BCP derivatives

Mukaiyama reagent-promoted metal-free preparation of alkynyl sulfones and phosphonates under mild conditions

An efficient and mild route for the formation sulfur or phosphor-substituted alkynes was herein demonstrated. The Mukaiyama reagent-mediated transformation started from easily-accessible substrates without carbon-carbon triple bonds, and the reaction proceeded under mild conditions (room temperature) in a one-pot manner, requiring for no transition metal-catalysts. The practical protocol featured for good functional groups tolerance (up to 41 examples) and high efficiency (up to 91% yields) towards alkynyl sulfones and alkynyl phosphonates at low cost.