82815-86-9

Basic information

• Product Name: (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER
• Synonyms: (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER
• CAS NO: 82815-86-9
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 210.23
• Mol File: 82815-86-9.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER(82815-86-9)
• EPA Substance Registry System: (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER(82815-86-9)

Safety Data

• Hazardous Substances Data: 82815-86-9(Hazardous Substances Data)

Usage

General Description

(3-Methoxyphenoxy) acetic acid ethyl ester is a chemical compound with the molecular formula C11H14O4. It is an ethyl ester derivative of (3-methoxyphenoxy) acetic acid, which is commonly used as an herbicide. (3-METHOXYPHENOXY) ACETIC ACID ETHYL ESTER is often used in agricultural settings to control the growth of weeds and unwanted vegetation. It works by disrupting the growth and development of plant cells, ultimately leading to their death. It is also used in research and industrial settings as a chemical intermediate in the synthesis of other compounds. (3-Methoxyphenoxy) acetic acid ethyl ester should be handled and used with caution, as it may be harmful if ingested, inhaled, or comes into contact with the skin or eyes.

Upstream product

• 64-17-5 ethanol 
• 2088-24-6 3-methoxyphenoxyacetic acid 
• 150-19-6 O-methylresorcine 
• 105-36-2 ethyl bromoacetate 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 2088-24-6 3-methoxyphenoxyacetic acid 
• 198905-40-7 2-(3-methoxyphenoxy)acetamide 
• 436155-36-1 2-(3-methoxyphenoxy)acetylhydrazine 
• 213749-49-6 4-(3-methoxy-phenoxy)-acetoacetic acid ethyl ester 
• 47093-11-8 N,N-Diethyl-N'-<(3-methoxy-phenoxy)-acetyl>-ethylendiamin 
• 15267-79-5 (3-Methoxy-phenoxy)-acethydroxamsaeure 
• 71706-78-0 4-(3-methoxy-phenoxy)-2-phenyl-acetoacetic acid amide 
• 857796-30-6 [4-(3-methoxy-phenoxymethyl)-2,5-dioxo-imidazolidin-4-yl]-acetic acid ethyl ester 
• 161952-02-9 Potassium 2-methoxy-4-(ethoxycarbonylmethoxy)phenylsulfonate 
• 1050426-29-3 2-(3-methoxy-phenoxy)-3-oxo-succinic acid diethyl ester 

Relevant articles and documents

Expedient discovery for novel antifungal leads: 1,3,4-Oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment

Developing novel fungicide candidates are intensively promoted by the rapid emergences of resistant fungi that outbreak on agricultural production. Aiming to discovery novel antifungal leads, a series of 1,3,4-oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment were constructed for evaluating their inhibition effects against phytopathogenic fungi in vitro and in vivo. Systematically structural optimizations generated the bioactive molecule I32 that was identified as a promising inhibitor against Rhizoctonia solani with the in vivo preventative effect of 58.63% at 200 μg/mL. The observations that were captured by scanning electron microscopy and transmission electron microscopy demonstrated that the bioactive molecule I32 could induce the sprawling growth of hyphae, the local shrinkage and rupture on hyphal surfaces, the extreme swelling of vacuoles, the striking distortions on cell walls, and the reduction of mitochondria numbers. The above results provided an indispensable complement for the discovery of antifungal lead bearing a quinazolin-4(3H)-one and 1,3,4-oxadiazole fragment.

Development of a Robust Protocol for the Synthesis of 6-Hydroxybenzofuran-3-carboxylic Acid

Benzofuran scaffolds are fundamental moieties found in a variety of biologically active natural products and synthetic drugs. In the course of one of our development programs, we needed to develop a practical and cost-effective manufacturing approach to such a benzofuran scaffold. Here we report a highly robust four-step, one-pot process that provides access to a 6-hydroxybenzofuran-3-carboxylic acid structure. An 1H NMR monitoring study allowed a better understanding of the overall sequence of events and the nature of the detected intermediates. After six steps, including the optimized tandem process, the desired hydroxylated benzofuran was obtained in 40% yield with a purity above 99%.

Design and Synthesis of New 1,3,4-Oxadiazole - Benzothiazole and Hydrazone Derivatives as Promising Chemotherapeutic Agents

Looking for new cytotoxic and antimicrobial agents with improved antitumor activity, a series of hydrazide and oxadiazole derivatives were designed and synthesized using 3-methoxyphenol as starting substance. Novel N'-(arylidene)-2-(3-methoxyphenoxy)aceto