82816-76-0

Basic information

• Product Name: BOC-PHE-PHE-GLY-OH
• Synonyms: BOC-PHE-PHE-GLY-OH;N-T-boc-phe-phe-gly;N-(tert-butoxycarbonyl)-Phe-Phe-Gly;Boc-Phe-Phe-Gly;Boc-FFG-OH
• CAS NO: 82816-76-0
• Molecular Formula: C₂₅H₃₁N₃O₆
• Molecular Weight: 469.53
• Mol File: 82816-76-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 135-137 °C
• Boiling Point: 793.4°C at 760 mmHg
• Flash Point: 433.7°C
• Appearance: /
• Density: 1.222g/cm³
• Vapor Pressure: 1.52E-26mmHg at 25°C
• Refractive Index: 1.566
• Storage Temp.: −20°C
• PKA: 3.33±0.10(Predicted)
• CAS DataBase Reference: BOC-PHE-PHE-GLY-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-PHE-PHE-GLY-OH(82816-76-0)
• EPA Substance Registry System: BOC-PHE-PHE-GLY-OH(82816-76-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 82816-76-0(Hazardous Substances Data)

Usage

General Description

The chemical "BOC-PHE-PHE-GLY-OH" is a peptide with a specific sequence of amino acids. The BOC group at the N-terminus serves as a protecting group to prevent unwanted reactions during peptide synthesis. The sequence "PHE-PHE-GLY" consists of the amino acids phenylalanine, phenylalanine, and glycine, which are commonly found in proteins and have unique properties and functions within biological systems. The "OH" at the C-terminus indicates that the peptide has a free carboxyl group, allowing it to participate in further chemical reactions. Overall, "BOC-PHE-PHE-GLY-OH" represents a specific sequence of amino acids with potential applications in biochemistry, medicine, and pharmaceutical research.

InChI:InChI=1/C25H31N3O6/c1-25(2,3)34-24(33)28-20(15-18-12-8-5-9-13-18)23(32)27-19(22(31)26-16-21(29)30)14-17-10-6-4-7-11-17/h4-13,19-20H,14-16H2,1-3H3,(H,26,31)(H,27,32)(H,28,33)(H,29,30)

Upstream product

• 66876-64-0 Boc-Phe-Phe-Gly-OMe 
• 62307-54-4 Boc-Phe-Phe-Gly-OEt 
• 139152-00-4 Boc-Phe-Phe-Gly-ONb 
• 64698-97-1 Boc-Phe-Phe-Gly-OBzl 
• 40099-25-0 Boc-Phe-Phe-NH-NH₂ 
• 56-40-6 glycine 
• 13122-89-9 (S)-methyl 2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-phenylpropanoate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 7625-57-2 methyl 2-((2S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)acetate 
• 139151-99-8 H-Phe-Gly-ONb*HCl 
• 30189-51-6 ethyl (N-tert-butoxycarbonyl-L-phenylalanyl)glycinate 
• 41041-68-3 L-phenylalanyl-glycine ethyl ester*HCl 

Downstream Products

• 73148-99-9 N-t-Boc-Phe-Phe-Gly-Leu-Met-NH₂ 
• 141540-42-3 Boc-(Phe)2-Gly-(Sar)2-OMe 
• 141540-34-3 Boc-(Phe)2-Gly-Sar-Gly-OEt 
• 103929-11-9 Boc-Phe-Phe-Gly-His-Met-NH₂ 
• 97731-67-4 N-t-Boc-Phe-Phe-Gly-Leu-Cys(Asm)-NH₂ 
• 1025882-52-3 Boc-Phe-Phe-Gly-Phe-Phe-Gly-OMe 
• 55572-15-1 L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methionine carboxamide hydrochloride 
• 160693-43-6 Boc-Asp(OBzl)-Phe-Phe-Gly-Leu-Met-NH₂ 
• 102996-89-4 p-Glu-Phe-Phe-Gly-His-Met-NH₂ 
• 97731-60-7 (4R,7R)-7-Amino-6-oxo-[1,2,5]dithiazocane-4-carboxylic acid {(S)-1-[(S)-1-({[(S)-1-((S)-1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-2-phenyl-ethyl}-amide 
• 103929-12-0 H-Phe-Phe-Gly-His-Met-NH₂*2HCl 
• 97721-63-6 N-t-Boc-(S-Acm)Cys-Phe-Phe-Gly-Leu-Met-NH₂ 
• 97731-61-8 ((4R,7R)-4-{(S)-1-[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-6-oxo-[1,2,5]dithiazocan-7-yl)-carbamic acid tert-butyl ester 
• 97721-56-7 N-t-Boc-(S-Acm)Cys-(S-Acm)Cys-Phe-Phe-Gly-Leu-Met-NH₂ 

Relevant articles and documents

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SYNTHESIS OF A NUMBER OF COMBINED ANALOGUES OF SUBSTANCE P AND LITORIN

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SYNTHESIS OF FOUR ANALOGS OF 6-11 SUBSTANCE P FRAGMENT OF INCREASED WATER SOLUBILITY

Four analogs of 6-11 Substance P fragment with histidine in various positions were synthesized by the conventional method.The peptides obtained exhibit a 100-200 times higher solubility in water than 6>SP6-11 analog, but only on