82859-04-9Relevant articles and documents
Synthesis in the Diazasteroid Group. XVIII. Syntheses of the 9,17-Diazasteroid System
Matoba, Katsuhide,Fukushima, Akiko,Takahata, Hiroki,Hirai, Yoshiro,Yamazaki, Takao
, p. 1300 - 1306 (2007/10/02)
A 9,17-diazasteroid system, I, was synthesized from an aminoester, III, and cyclohexanone.Unfortunately the yield was poor.Another 9,17-diazasteroid system, II, was prepared from the condensation product, XVa, of quinoline N-oxide with an active methine compound, IV.Thus, XVa was hydrolyzed, followed by decarboxylation, reduction and cyclization.The yield in each step to II was moderate.Keywords- azasteroid; diazasteroid; quinoline N-oxide; cyclization; Pictet-Spengler reaction; active methylene compound; pyrrolopyridine; quinolylpyrrolidine