829-40-3

Basic information

• Product Name: 1-(2-FLUOROPHENYL)-2-NITROPROPENE
• Synonyms: 2'-FLUORO-BETA-METHYL-BETA-NITROSTYRENE;1-(2-FLUOROPHENYL)-2-NITROPROPENE;Benzene,1-fluoro-2-(2-nitro-1-propen-1-yl)-;1-Fluoro-2-(2-nitropropenyl)benzene;Benzene, 1-fluoro-2-(2-nitro-1-yl) -;1-fluoro-2-(2-nitroprop-1-enyl)benzene
• CAS NO: 829-40-3
• Molecular Formula: C₉H₈FNO₂
• Molecular Weight: 181.16
• Product Categories: Propanes/propenes
• Mol File: 829-40-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 43-44℃
• Boiling Point: 262.2°C at 760 mmHg
• Flash Point: 112.4°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 0.018mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 1-(2-FLUOROPHENYL)-2-NITROPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-FLUOROPHENYL)-2-NITROPROPENE(829-40-3)
• EPA Substance Registry System: 1-(2-FLUOROPHENYL)-2-NITROPROPENE(829-40-3)

Safety Data

• Hazardous Substances Data: 829-40-3(Hazardous Substances Data)

Usage

General Description

1-(2-Fluorophenyl)-2-nitropropene is a chemical compound with the molecular formula C9H8FNO2. It is a nitroalkene derivative with a nitro group located on the second carbon of the propene chain. 1-(2-FLUOROPHENYL)-2-NITROPROPENE is a yellow solid with a melting point of 75-77 degrees Celsius and is soluble in organic solvents. It is used in organic synthesis and is a precursor in the production of various pharmaceuticals and agrochemicals. The presence of the fluorophenyl and nitro groups makes it a versatile building block for the synthesis of complex organic molecules. However, its use and handling require careful attention to safety precautions due to its potential hazards and toxicity.

InChI:InChI=1/C9H8FNO2/c1-7(11(12)13)6-8-4-2-3-5-9(8)10/h2-6H,1H3/b7-6+

Upstream product

• 79-24-3 Nitroethane 
• 446-52-6 2-Fluorobenzaldehyde 
• 222025-84-5 1-(o-fluorophenyl)-2-nitro-1-propanol 
• 89-99-6 2-fluorobenzylamine 

Downstream Products

• 2836-82-0 (o-fluorophenyl)acetone 
• 222026-16-6 3-(2-fluoro-phenyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 222026-76-8 3-(2-fluoro-phenyl)-1,4-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 222026-81-5 1-allyl-3-(2-fluoro-phenyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 222026-91-7 1-benzyl-3-(2-fluoro-phenyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 21906-05-8 3-(2'-fluorophenyl)butan-2-one 
• 21894-65-5 2-(o-Fluorphenyl)-3-butylamin 
• 1314922-08-1 1-fluoro-2-(2-nitropropyl)benzene 
• 945538-82-9 4-(2-fluorophenyl)-5-hydroxy-5-methyl-1,5-dihydro-2H-pyrrol-2-one 

Relevant articles and documents

Substrate promiscuity of ortho-naphthoquinone catalyst: Catalytic aerobic amine oxidation protocols to deaminative cross-coupling and n-nitrosation

ortho-Naphthoquinone-based organocatalysts have been identified as versatile aerobic oxidation catalysts. Primary amines were readily cross-coupled with primary nitroalkanes via deaminative pathway to give nitroalkene derivatives in good to excellent yields. Secondary and tertiary amines were inert to ortho-naphthoquinone catalysts; however, secondary nitroalkanes were readily converted by ortho-naphthoquinone catalysts to the corresponding nitrite species that in situ oxidized the amines to the corresponding N-nitroso compounds. Without using harsh oxidants in a stoichiometric amount, the present catalytic aerobic oxidation protocol utilizes the substrate promiscuity feature to provide a facile access to amine oxidation products under mild reaction conditions.

Clean five-step synthesis of an array of 1,2,3,4-tetra-substituted pyrroles using polymer-supported reagents

Polymer-supported reagents and other solid sequestering agents may be used to generate an array of 1,2,3,4-tetra-substituted pyrrole derivatives without any chromatographic purification step.