829-45-8

Basic information

• Product Name: 3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER
• Synonyms: AKOS BC-1960;3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER;METHYL 3-OXO-3-(4-PYRIDINYL)PROPANOATE;Methyl 3-(4-Pyridyl)-3-oxopropanoate;Methyl 3-oxo-3-(4-pyridyl)propanoate;Methyl 3-oxo-3-(pyridin-4-yl)
• CAS NO: 829-45-8
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.17266
• Mol File: 829-45-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 65-68 °C
• Boiling Point: 276.491°C at 760 mmHg
• Flash Point: 121.018°C
• Appearance: /
• Density: 1.189g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.515
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 8.59±0.25(Predicted)
• CAS DataBase Reference: 3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER(829-45-8)
• EPA Substance Registry System: 3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER(829-45-8)

Safety Data

• Hazardous Substances Data: 829-45-8(Hazardous Substances Data)

Usage

General Description

3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER is a chemical compound with the molecular formula C10H11NO3. It is an ester of 3-oxo-3-pyridin-4-yl-propionic acid, a derivative of pyridine. It is commonly used in the pharmaceutical industry as a precursor for the synthesis of various pharmaceutical drugs. 3-OXO-3-PYRIDIN-4-YL-PROPIONIC ACID METHYL ESTER has a variety of biological activities and is used in the development of anti-inflammatory, analgesic, and antipyretic drugs. Additionally, it has potential applications in the field of medicinal chemistry for the development of new therapeutic agents. However, it is important to handle this chemical with care as it may pose hazards to health and the environment if not properly managed and utilized.

InChI:InChI=1/C9H9NO3/c1-13-9(12)6-8(11)7-2-4-10-5-3-7/h2-5H,6H2,1H3

Upstream product

• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 79-20-9 acetic acid methyl ester 
• 75399-11-0 (Z)-3-Hydroxy-3-pyridin-4-yl-acrylic acid methyl ester 
• 1122-54-9 methyl (4-pyridyl) ketone 
• 616-38-6 carbonic acid dimethyl ester 
• 125280-29-7 (4S,5R)-5-allyl-2,2-dimethyl-4-(3-pyridyl)-1,3-dioxane 
• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 108-21-4 Isopropyl acetate 
• 55-22-1 pyridine-4-carboxylic acid 
• 38330-80-2 monomethyl monopotassium malonate 

Downstream Products

• 841-97-4 7-Methoxy-4-(4)-pyridyl-cumarin 
• 92906-36-0 7-hydroxy-4-(pyridin-4-yl)-2H-chromen-2-one 
• 913375-88-9 1-methyl-2-phenyl-5-(pyridin-4-yl)-1,2-dihydropyrazol-3-one 
• 913375-90-3 1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1H-pyrazole-4-carboxylic acid 
• 913375-89-0 1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1H-pyrazole-4-carbaldehyde 
• 329325-40-8 1-(pyridine-4-yl)propane-1,3-diol 

Relevant articles and documents

PHOSPHORUS-CONTAINING PRODRUGS OF GEMCITABINE

This invention relates to phosphorus-containing prodrugs of gemcitabine and their use in the treatment of cancer and viral infectious diseases. Compared with the parent drug (i.e., Gemcitabine), the prodrugs of present invention show a significant overall

Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: Synthesis of α,α-disubstituted dihydropyrroles and studies towards an asymmetric protocol

We report efficient Pd-catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes as the basis of a general entry to α,α-disubstituted pyrrolidine derivatives. We also demonstrate that catalytic asymmetric variants of this chemistry are feasible by employing a suitable chiral ligand. The Royal Society of Chemistry 2013.

PROCESS FOR THE PREPARATION OF 3-(4-PYRIDINYL)-PROPANOL AND INTERMEDIATES USEFUL IN ITS SYNTHESIS

A process for the preparation of 3-(4-pyridinyl)-propanol or a salt thereof and intermediates useful in its synthesis.