829-84-5

Basic information

• Product Name: DICYCLOHEXYLPHOSPHINE
• Synonyms: DICYCLOHEXYLPHOSPHINE;dicyclohexyl-phosphin;Dicyclohexylphosphine,98%;Dicyclohexylphosphine,98%(10wt%inhexane);DICYCLOHEXYLPHOSPHINE (10% WT. IN HEXANE);Bis(cyclohexyl)phosphine;dicyclohexylphosphane;98% Cy2PH
• CAS NO: 829-84-5
• Molecular Formula: C₁₂H₂₃P
• Molecular Weight: 198.28
• EINECS: 212-590-9
• Product Categories: Secondary Phosphines;Catalysis and Inorganic Chemistry;Phosphorus Compounds;Phosphorus Precursors;organophosphorus ligand
• Mol File: 829-84-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: 2°C
• Boiling Point: 129 °C 8 mm Hg
• Flash Point: 2 °C
• Appearance: Colorless Liquid
• Density: 0,98 g/cm3
• Vapor Pressure: 0.00373mmHg at 25°C
• Refractive Index: n 20/D 1.516
• Sensitive: air sensitive
• CAS DataBase Reference: DICYCLOHEXYLPHOSPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: DICYCLOHEXYLPHOSPHINE(829-84-5)
• EPA Substance Registry System: DICYCLOHEXYLPHOSPHINE(829-84-5)

Safety Data

• Hazard Codes: F,T
• Statements: 17-23/24/25
• Safety Statements: 17-36/37/39-45
• RIDADR: UN 2845 4.2/PG 1
• TSCA: No
• Hazardous Substances Data: 829-84-5(Hazardous Substances Data)

Usage

General Description

Dicyclohexylphosphine is a chemical compound with the molecular formula C12H23P. It is a white solid at room temperature and is commonly used as a ligand in organometallic chemistry. Dicyclohexylphosphine is a strong donor of electron density, and its bulky nature allows it to stabilize metal centers in catalytic reactions. It is also often used in the synthesis of various organometallic complexes and as a reducing agent in organic synthesis. Additionally, dicyclohexylphosphine has been studied for its potential use in pharmaceutical and medicinal applications, showing promise as a versatile building block in the preparation of new drugs. Overall, dicyclohexylphosphine plays a crucial role in the field of organometallic chemistry and has a wide range of applications in both academic research and industrial processes.

InChI:InChI=1/C12H23P/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h11-13H,1-10H2

Upstream product

• 15873-72-0 dicyclohexylphosphinoyl chloride 
• 3676-98-0 tetracyclohexyl-diphosphane-P,P'-disulfide 
• 931-51-1 cyclohexylmagnesiumchloride 
• 19966-81-5 lithium dicyclohexylphosphide 
• 110-83-8 cyclohexene 
• 16523-54-9 chlorodicyclohexylphosphane 
• 14717-29-4 dicyclohexylphosphine oxide 
• 931-50-0 cyclohexylmagnesium bromide 
• 38169-30-1 dicyclohexylthiophosphinic acid chloride 
• 7439-96-5 manganese 
• 201230-82-2 carbon monoxide 
• 80413-46-3 Ethyl-dicyclohexylphosphinit 

Downstream Products

• 832-39-3 dicyclohexylphosphinic acid 
• 93189-63-0 Dicyclohexyl-ethoxycarbonylmethyl-phosphin 
• 23743-26-2 1,2-bis-(dicyclohexylphosphino)ethane 
• 52054-27-0 1-cyclohexyl-phospholane 
• 96679-14-0 Hydroxymethyl-dicyclohexyl-phosphinsulfid 
• 34729-69-6 dicyclohexyl(hydroxymethyl)phosphine oxide 
• 58395-72-5 dicyclohexyl-bis(hydroxymethyl)phosphonium chloride 
• 96377-46-7 1,5-bis-(dicyclohexylphosphino)-pentane 
• 94710-82-4 Dicyclohexyl-(2-ethoxycarbonyl-ethyl)-phosphin 
• 66830-54-4 Dimethylaminomethyl-dicyclohexylphosphin 
• 3875-20-5 Carbamoyl-dicyclohexyl-phosphin 
• 15389-64-7 <1-Dicyclohexyl-phosphino-1-methyl-ethyl>-triphenyl-phosphonium-tetraphenyloborat 
• 2359-99-1 tetracyclohexyldiphosphine 
• 135492-10-3 Dicyclohexyl(tetrahydropyranyl-2-methyl)phosphan 

Relevant articles and documents

Copper-catalyzed C–P cross-coupling of secondary phosphines with (hetero)aromatic bromide

A novel and convenient approach to the synthesis of various tertiary phosphines via a copper-catalyzed cross-coupling of (hetero)aromatic bromide with secondary phosphines has been developed. The reaction employs cheap copper as the catalyst, 2,6-bis(N-methylaminomethyl)pyridine (L4) as a perfect ligand and KOtBu as a base; all reactions are carried out under argon atmosphere. A variety of sterically hindered and/or functionalized substrates were found to react under these reaction conditions to provide products in good to excellent yields. Moreover, ten new tertiary phosphines were first reported in this process.

Photo-initiator 2,4,6-trimethylbenzoyldicyclohexyloxyphosphine and preparation method and application thereof

The invention relates to a preparation method of a photo-initiator 2,4,6-trimethylbenzoyldicyclohexyloxyphosphine.Under the protection of argon, dicyclohexyl phosphine oxide, metallic sodium and tertiary butanol are reacted in methylbenzene solution to obtain intermediate I; the intermediate I is reacted with 2,4,6-trimethylbenzoyl chloride to obtain intermediate II; the intermediate II is reacted with hydrogen peroxide at 30-35 DEG C to obtain 2,4,6-trimethylbenzoyldicyclohexyloxyphosphine, and liquid phase purity is up to 99.21%.The preparation method is simple to perform and advanced, a solvent is recyclable, and the method is easy for industrial production.

Reduction of phosphinites, phosphinates, and related species with DIBAL-H

Diisobutylaluminium hydride has been found to be an excellent reducing agent for phosphinites, phosphinates, and chlorophosphines. By performing reductions in situ, direct synthesis of secondary phosphine boranes from Grignard reagents has been achieved without isolation or purification of any intermediates. Georg Thieme Verlag Stuttgart.