82923-95-3

Basic information

• Product Name: (S)-1-(4-Carboxy-2-methyl-pentanoyl)-2,3-dihydro-1H-indole-2-carboxylic acid
• CAS NO: 82923-95-3
• Molecular Weight: 305.331
• Mol File: 82923-95-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(4-Carboxy-2-methyl-pentanoyl)-2,3-dihydro-1H-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-Carboxy-2-methyl-pentanoyl)-2,3-dihydro-1H-indole-2-carboxylic acid(82923-95-3)
• EPA Substance Registry System: (S)-1-(4-Carboxy-2-methyl-pentanoyl)-2,3-dihydro-1H-indole-2-carboxylic acid(82923-95-3)

Safety Data

• Hazardous Substances Data: 82923-95-3(Hazardous Substances Data)

Upstream product

• 4295-92-5 (+/-)-anti-2,4-dimethylglutaric anhydride 
• 82923-76-0 (S)-5-methoxyindol-2,3-dihydro-2-carboxylic acid hydrochloride 

Relevant articles and documents

Angiotensin Converting Enzyme Inhibitors: 1-Glutarylindoline-2-carboxylic Acid Derivatives

The preparation of a series of 1-glutarylindoline-2(S)-carboxylic acid derivatives, 6a-v and 21a-c, is described.The above compounds were tested for inhibition of angiotensin converting enzyme.The structure-activity relationship of the series is also discussed.Compound 6u, the most potent member of the series, had an in vitro IC50 of 4.8*10-9 M.Compound 6v, an ethyl ester of 6u, lowered blood pressure 70 mm in spontaneous hypertensive rats at an oral dose of 30 mg/kg.