82924-23-0

Basic information

• Product Name: ethyl 1-(4-carboethoxy-4R-phenethylbutanoyl)-indoline-2S-carboxylate
• Synonyms: ethyl 1-(4-carboethoxy-4R-phenethylbutanoyl)-indoline-2S-carboxylate
• CAS NO: 82924-23-0
• Molecular Weight: 437.536
• Mol File: 82924-23-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 1-(4-carboethoxy-4R-phenethylbutanoyl)-indoline-2S-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(4-carboethoxy-4R-phenethylbutanoyl)-indoline-2S-carboxylate(82924-23-0)
• EPA Substance Registry System: ethyl 1-(4-carboethoxy-4R-phenethylbutanoyl)-indoline-2S-carboxylate(82924-23-0)

Safety Data

• Hazardous Substances Data: 82924-23-0(Hazardous Substances Data)

Upstream product

• 18496-54-3 phenylbutyric acid chloride 
• 82924-24-1 (R)-1-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-2-phenethyl-pent-4-en-1-one 
• 82924-16-1 1-(4-phenylbutyryl)-L-prolinol 
• 82924-25-2 ethyl 2R-allyl-4phenyl-butyrate 
• 79854-42-5 Ethyl (S)-indoline-2-carboxylate hydrochloride 
• 82924-27-4 ethyl hydrogen (4R)-4-(2-phenylethyl)glutarate 
• 82923-84-0 3-Phenethyl-dihydro-pyran-2,6-dione 
• 62953-19-9 2-phenethyl-glutaric acid 
• 127983-06-6 4R-carboethoxy-6-phenyl-hexanoic acid 

Downstream Products

• 82924-28-5 1-(4-carboethoxy-4R-phenethylbutanoyl)-indoline-2S-carboxylic acid 
• 82924-29-6 1-(4-carboxy-4R-phenethylbutanoyl)-indoline-2S-carboxylic acid 
• 82923-85-1 (S)-1-(4-Carboxy-6-phenyl-hexanoyl)-2,3-dihydro-1H-indole-2-carboxylic acid 

Relevant articles and documents

Angiotensin Converting Enzyme Inhibitors: 1-Glutarylindoline-2-carboxylic Acid Derivatives

The preparation of a series of 1-glutarylindoline-2(S)-carboxylic acid derivatives, 6a-v and 21a-c, is described.The above compounds were tested for inhibition of angiotensin converting enzyme.The structure-activity relationship of the series is also discussed.Compound 6u, the most potent member of the series, had an in vitro IC50 of 4.8*10-9 M.Compound 6v, an ethyl ester of 6u, lowered blood pressure 70 mm in spontaneous hypertensive rats at an oral dose of 30 mg/kg.