82954-66-3

Basic information

• Product Name: (S)-4-<(N-Benzyloxycarbonyl-(S)-alanyl)aminomethyl>-2,2-dimethyl-1,3-dioxolan
• CAS NO: 82954-66-3
• Molecular Weight: 336.388
• Mol File: 82954-66-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-<(N-Benzyloxycarbonyl-(S)-alanyl)aminomethyl>-2,2-dimethyl-1,3-dioxolan(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-<(N-Benzyloxycarbonyl-(S)-alanyl)aminomethyl>-2,2-dimethyl-1,3-dioxolan(82954-66-3)
• EPA Substance Registry System: (S)-4-<(N-Benzyloxycarbonyl-(S)-alanyl)aminomethyl>-2,2-dimethyl-1,3-dioxolan(82954-66-3)

Safety Data

• Hazardous Substances Data: 82954-66-3(Hazardous Substances Data)

Upstream product

• 1142-20-7 N-Cbz-Ala 
• 22195-47-7 4-aminomethyl-2,2-dimethyl[1,3]dioxolane 

Downstream Products

• 82954-62-9 N-Benzyloxycarbonyl-(S)-alanin-<(S)-2,3-dihydroxypropylamid> 

Relevant articles and documents

N-Acylation of 3-Amino-1,2-propanediol with Amino Acids

Racemic 3-amino-1,2-propanediol was selectively N-acylated by several Z (S)-amino acids using 1,1'-carbonyldiimidazole as coupling reagent and tetrahydrofuran as solvent.In some cases (alanine, valine, phenylalanine) one of the two diastereomeric amides formed precipitates spontaneously and can be easily separated.In the case of alanine, the S,S-configuration of the isolated amide was proved.The protective Z groups were removed by catalytic hydrogenation to yield the hydrophilic oily amides.