83-31-8

Basic information

• Product Name: 1,8-Naphthosultone
• Synonyms: naphth[1,8-cd]-1,2-oxathiole,2,2-dioxide;naphthosultone;1-naphthol-8-sulf. acid sultone;1-NAPHTHOL-8-SULF. ACID SULTONE, MOIST. WITH H2O (H2O ~50%);8-Hydroxy-1-naphthalenesulfonic acid, γ-sultone;1-Naphthol-8-sulfonic acid sultone, 8-Hydroxynaphthalene-1-sulfonic acid sultone;1,8-Naphthasultone;1,8-Naphthosulfone
• CAS NO: 83-31-8
• Molecular Formula: C10H6O3S
• Molecular Weight: 206.22
• EINECS: 201-468-0
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 83-31-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 154-157 °C (dec.)(lit.)
• Boiling Point: 419.524 °C at 760 mmHg
• Flash Point: 207.521 °C
• Appearance: light yellow crystal
• Density: 1.556g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.729
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 9381
• CAS DataBase Reference: 1,8-Naphthosultone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthosultone(83-31-8)
• EPA Substance Registry System: 1,8-Naphthosultone(83-31-8)

Safety Data

• Hazard Codes: Xi
• Statements: 38
• Safety Statements: 22-28
• WGK Germany: 3
• Hazardous Substances Data: 83-31-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H6O3S/c11-14(12)9-6-2-4-7-3-1-5-8(13-14)10(7)9/h1-6H

Upstream product

• 64-17-5 ethanol 
• 20653-35-4 8-sulfonato-1-naphthalenediazonium zwitterion 
• 117-22-6 8-hydroxy-naphthalene-1-sulfonic acid 
• 103708-12-9 8-Hydroxy-naphthalene-1-sulfonic acid benzylamide 
• 82-75-7 8-anilino-1-naphthalenesulfonate 
• 7664-93-9 sulfuric acid 
• 7732-18-5 water 

Downstream Products

• 861048-17-1 6-benzoyl-naphth[1,8-cd][1,2]oxathiol-2,2-dioxide 
• 408351-97-3 6-(toluene-4-sulfonyl)-naphth[1,8-cd][1,2]oxathiol-2,2-dioxide 
• 6837-95-2 1-Naphthol-8-sulfonamid 
• 117-22-6 8-hydroxy-naphthalene-1-sulfonic acid 
• 84912-13-0 2,2-dioxo-2λ⁶-naphth[1,8-cd][1,2]oxathiol-6-sulfonic acid 
• 103708-12-9 8-Hydroxy-naphthalene-1-sulfonic acid benzylamide 
• 569-42-6 1,8-dihydroxynaphthalene 
• 91586-81-1 6-Nitronaphth<1,8-cd>-1,2-oxathiole S,S-dioxide 
• 431079-36-6 (2H)-5-benzyloxy-2,3-dihydrospiro[naphthalene-1(4H),2'-naphtho[1,8-de][1,3]dioxin] 
• 431079-21-9 (2H)-4'-acetoxy-5-benzyloxy-2,3-dihydrospiro[naphthalene-1(4H),2'-naphtho[1,8-de][1,3]dioxin] 
• 5002-73-3 ZGlyPheONa 

Relevant articles and documents

Sulfonation of a series of naphthalenes containing two different oxy substituents

The reactions of a series of α,α- and β,β-disubstituted naphthalenes containing two different substituents OR1 (R1 = H, SO2CH3) and OR2 (R2 =CH3, SO2CH3) with sulfur trioxide in CD3NO2 has been studied.The electronic directing effect of the hydroxy group was found to be dominant over that of the methoxy group, which in turn dominates that of the mesyloxy group.Upon reaction with an excess of sulfur trioxide, the hydroxy group is, at least in part, sulfated.For the β-hydroxy-β-methoxynaphthalenes 3a-5a and for 3-mesyloxy-2-naphthol (3c) especially, hydrogen sulfate formation strongly influences the product mixture composition.Thus, upon reaction with 1.0 equiv of SO3, 7-methoxy-2-naphthol (5a) yields its 1-sulfonic acid (1-S), whereas upon reaction with 2.0 equiv, it is the 8-S that is mainly formed due to initial hydrogen sulfate formation.Furthermore, sulfonic acid isomerizations due to steric hindrance are observed.Upon using >2.0 equiv of SO3, formation of di- and trisulfonic acids, as well as sulfo derivatives of both 8,1-naphthalenesultone and the cyclic naphthalene-1-sulfonate-2-sulfate anhydride is observed.

Approaches to anthracyclines: Efficient syntheses of substituted naphthylacetonitriles

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